# Idiopathic Eosinophilic Cholecystitis in the Setting of Cholelithiasis: A Case Report and Brief Literature Review

**Authors:** Smara Sigdel, Stephen Wilson, Elaria Habib, John Diks

PMC · DOI: 10.7759/cureus.89424 · 2025-08-05

## TL;DR

A 69-year-old woman was diagnosed with a rare gallbladder condition after presenting with symptoms resembling acute cholecystitis.

## Contribution

This case report adds to the limited literature on idiopathic eosinophilic cholecystitis and emphasizes its diagnostic challenges.

## Key findings

- EC was diagnosed through histopathological examination after initial suspicion of acute cholecystitis.
- The case highlights the importance of considering EC in differential diagnoses of gallbladder inflammation.
- Clinical presentation alone is insufficient for diagnosing EC due to its similarity with other gallbladder conditions.

## Abstract

Eosinophilic cholecystitis (EC) is a rare inflammatory condition characterized by prominent eosinophilic infiltration of the gallbladder wall. It often mimics typical acute cholecystitis and is usually diagnosed only after histopathological examination. This case report discusses a 69-year-old woman presenting with symptoms of acute cholecystitis who was later found to have EC. The report highlights the clinical presentation, diagnosis, treatment, and relevant literature on this uncommon condition.

## Linked entities

- **Diseases:** acute cholecystitis (MONDO:0002155)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), EC (MESH:D002764), acute cholecystitis (MESH:D041881), Cholelithiasis (MESH:D002769)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12323892/full.md

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Source: https://tomesphere.com/paper/PMC12323892