# Association of childhood socioeconomic status and health with depressive symptoms in later life: a cross-sectional latent class analysis of the 2014/2015 Indonesia Family Life Survey

**Authors:** Ronny Isnuwardana, Jonathan Gibson, Asri Maharani, Herni Susanti, Helen Brooks, Penny Bee, Laura Anselmi

PMC · DOI: 10.1136/bmjopen-2024-095197 · 2025-08-04

## TL;DR

This study finds that childhood socioeconomic and health disadvantages in Indonesia are linked to higher depressive symptoms in adulthood, highlighting the need for early interventions.

## Contribution

The study provides novel evidence from Indonesia on the long-term mental health impacts of childhood socioeconomic and health disadvantages in a low-income setting.

## Key findings

- Three classes of childhood disadvantage were identified, with moderate and high disadvantage linked to increased odds of depressive symptoms.
- Adjustments for adult factors like education and wealth did not eliminate the association between early disadvantage and depressive symptoms.
- The findings suggest a need for child-focused interventions to reduce long-term mental health risks in low-income countries.

## Abstract

While childhood circumstances predict mental health outcomes in high-income countries, evidence from low-income and middle-income countries (LMICs) like Indonesia remains scarce. This study examines the long-term association between childhood socioeconomic status (SES), health and depressive symptoms in adulthood, testing the hypothesis that early-life disadvantages increase the odds of depressive symptoms later in life.

Cross-sectional analysis using latent class analysis to cluster childhood SES/health and logistic regression to assess associations with depressive symptoms.

A nationally representative household survey was conducted across 13 provinces in urban and rural areas of Indonesia.

32 085 adults aged 18 years and older from the 2014–2015 Indonesia Family Life Survey. Participants with missing data on childhood circumstances or depressive symptoms were excluded, resulting in a final analytic sample of 29 140 individuals.

The primary outcome was depressive symptoms measured using the 10-item Centre for Epidemiologic Studies Depression Scale, with scores ≥10 indicating clinically significant symptoms. Secondary exposures included latent classes of childhood SES and health (high, moderate and low disadvantage). Analyses adjusted for adult SES, health behaviours, social capital and demographic characteristics.

Three latent classes emerged: low (64.85%), moderate (5.73%) and high (29.42%) early-life disadvantage. Adjusted logistic regression showed higher odds of depressive symptoms for high (OR 1.39, 95% CI 1.28 to 1.50) and moderate disadvantage (OR 1.66, 95% CI 1.48 to 1.87) versus low. Significant covariates included age, education, wealth and social capital (all p<0.05).

Early-life disadvantages predict depressive symptoms in adulthood in Indonesia, underscoring the need for child-focused interventions (health, education and poverty reduction) to mitigate long-term mental health risks in LMICs. Further research should explore longitudinal mechanisms.

## Full-text entities

- **Diseases:** Depression (MESH:D003866)

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Source: https://tomesphere.com/paper/PMC12323512