# Simultaneous Placement of Multiple Airway Stents in Three Patients With Extensive Airway Stenosis: A Case Series

**Authors:** Shogo Toyama, Kohei Fujita, Naoki Fujimoto, Yuta Okada, Saiki Yoshimura, Kiminobu Tanizawa

PMC · DOI: 10.1002/rcr2.70311 · Respirology Case Reports · 2025-08-04

## TL;DR

This case series shows that placing multiple airway stents using flexible bronchoscopy can safely and effectively treat severe airway narrowing in patients with cancer or tracheomalacia.

## Contribution

The study demonstrates the safety and efficacy of simultaneous multiple SEMS placement via flexible bronchoscopy in patients with extensive airway stenosis.

## Key findings

- Multiple SEMS placement successfully relieved airway stenosis in three patients.
- The procedure improved oxygenation and reduced dyspnoea without major complications.
- This approach is a viable alternative when rigid bronchoscopy is not available.

## Abstract

Airway stenting is a critical therapeutic intervention for managing airway obstruction caused by both malignant and benign conditions. While Dumon Y‐stent placement is sometimes indicated for patients with extensive airway narrowing, facilities capable of performing rigid bronchoscopy are limited. In such cases, the use of multiple self‐expanding metallic stents (SEMS) via flexible bronchoscopy under local anaesthesia presents a valuable alternative. We report three cases in which multiple airway stents were placed simultaneously using this approach. Case 1 involved a patient with stage IV squamous cell lung cancer, in whom the primary tumour caused extrinsic tracheal compression and direct invasion of the right main bronchus. Cases 2 and 3 were diagnosed clinically with tracheomalacia. In all three cases, the placement of multiple SEMS successfully relieved airway stenosis, improved oxygenation, and reduced dyspnoea, without major complications. These cases support the potential of simultaneous multiple SEMS placement as a safe and effective therapeutic option for patients with extensive airway narrowing.

We report three cases in which multiple self‐expanding metallic stents (SEMS) were deployed using flexible bronchoscopy under local anaesthesia. In all cases, stent placement successfully relieved airway stenosis, improved oxygenation, and alleviated dyspnoea without major complications. These cases support the potential role of simultaneous multiple SEMS placement as a safe and effective therapeutic option for patients with extensive airway narrowing.

## Linked entities

- **Diseases:** squamous cell lung cancer (MONDO:0005097)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), airway obstruction (MESH:D000402), hypoxemia (MESH:D000860), sputum retention (MESH:D016055), COPD (MESH:D029424), impaired sputum (MESH:D060825), pneumothorax (MESH:D011030), polychondritis (MESH:D011081), airway collapse (MESH:D001261), pleural effusion (MESH:D010996), aspiration pneumonia (MESH:D011015), cancer (MESH:D009369), inflammatory (MESH:D007249), femoral neck fracture (MESH:D005265), bronchomalacia (MESH:D055091), respiratory failure (MESH:D012131), pleural dissemination (MESH:D010995), tracheomalacia (MESH:D055090), difficulties (MESH:D051346), obstructive pneumonia (MESH:D011014), tracheobronchomalacia (MESH:D055089), stage IV squamous cell lung cancer (MESH:D018307), cough (MESH:D003371), Airway Stenosis (MESH:D003251)
- **Chemicals:** oxygen (MESH:D010100), prednisolone (MESH:D011239), SEMS (-), steroid (MESH:D013256), methylprednisolone (MESH:D008775)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12322318/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12322318/full.md

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Source: https://tomesphere.com/paper/PMC12322318