# Case Report: A Mirror Within: Open Appendectomy in a Patient With Situs Inversus Totalis and Acute Appendicitis

**Authors:** Waleed Ahmad, Haadia Ali, Wasif Majeed Chaudhry, Javed Iqbal, Asraf Hussain

PMC · DOI: 10.1002/ccr3.70678 · Clinical Case Reports · 2025-08-04

## TL;DR

This case report discusses a rare instance of acute appendicitis in a patient with situs inversus totalis, emphasizing the importance of early diagnosis and imaging for successful treatment.

## Contribution

The novelty lies in highlighting the challenges and successful management of appendicitis in a patient with a rare anatomical condition.

## Key findings

- Acute appendicitis in situs inversus totalis can present in the left lower quadrant.
- Early imaging and recognition of anatomical differences are crucial for timely intervention.
- Proper diagnosis leads to optimal surgical outcomes in such rare cases.

## Abstract

In case of situs inversus totalis, acute appendicitis can develop in the left lower quadrant, and delayed diagnosis and complications can occur. Clinicians should be highly suspicious and should use imaging to confirm diagnosis. Detection of anatomical differences leads to intervening steps at an initial stage and optimal surgical success in peculiarities.

## Linked entities

- **Diseases:** acute appendicitis (MONDO:0005649), situs inversus totalis (MONDO:0010029)

## Full-text entities

- **Diseases:** dextrocardia (MESH:D003914), Rebound tenderness (MESH:D063806), bowel obstruction (MESH:D012778), pain (MESH:D010146), Meckel's diverticulitis (MESH:D004238), testicular (MESH:D013733), adhesions (MESH:D000267), epididymitis (MESH:D004823), acute appendicitis pain (MESH:D059787), fever (MESH:D005334), incarcerated (MESH:D060725), Acute Appendicitis (MESH:D001064), leukocytosis (MESH:D007964), vomiting (MESH:D014839), ectopic pregnancy (MESH:D011271), enteritis (MESH:D004751), Fluid (MESH:D002559), anorexia (MESH:D000855), midgut malrotation (MESH:C562456), Situs Inversus Totalis (MESH:D012857), ureteric colic (MESH:D056844), obese (MESH:D009765), abdominal pain (MESH:D015746), ruptured ovarian cyst (MESH:D010048), Meckel's diverticulum (MESH:D008467), hernia (MESH:D006547), psoas abscess (MESH:D016659), Congenital anomalies (MESH:D000013), intestinal failure (MESH:D000090124), nausea (MESH:D009325)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12321592/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12321592/full.md

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Source: https://tomesphere.com/paper/PMC12321592