# Cephalohematoma Infected With Staphylococcus epidermidis and Skull Abscess: A Case Report

**Authors:** Saeedeh Parvaresh, Maedeh Jafari, Shahryar Eslami, Fatemeh Karami Robati, Mohammad Ali Jafari

PMC · DOI: 10.1002/ccr3.70703 · Clinical Case Reports · 2025-08-04

## TL;DR

A rare case of a neonate with a cephalohematoma infected by Staphylococcus epidermidis and a skull abscess is reported, with successful treatment using antibiotics and drainage.

## Contribution

This is the first documented case of cephalohematoma infected with Staphylococcus epidermidis and associated skull abscess in a neonate.

## Key findings

- The neonate had a cephalohematoma infected with Staphylococcus epidermidis and a skull abscess.
- The infection was localized to the scalp without systemic complications like sepsis or meningitis.
- Treatment with intravenous antibiotics and abscess drainage led to successful recovery.

## Abstract

Cephalohematoma is a self‐limiting lesion in 1%–2% of neonates. Cephalohematoma bleeds between the bone and periosteum and is limited to cranial sutures. Complications of the cephalohematoma include hyperbilirubinemia and secondary infection. We describe a neonate with cephalohematoma cultures positive for 
S. epidermidis
 as well as progressive deepening of the skull. There was no evidence of systemic infection, such as sepsis, meningitis, or osteomyelitis. In the ultrasound and brain MRI, the abscess was restricted to the scalp without involvement of the brain parenchyma and osteomyelitis of the bone. After a short period of intravenous antibiotics and drainage of the abscess, the patient was discharged from the hospital. To our knowledge, this is the first report of cephalohematoma infected with Staphylococcus

epidermidis
 and skull abscess.

## Full-text entities

- **Diseases:** Skull Abscess (MESH:D000038), sepsis (MESH:D018805), osteomyelitis (MESH:D010019), Cephalohematoma Infected (MESH:D007239), hyperbilirubinemia (MESH:D006932), meningitis (MESH:D008580), bleeds (MESH:D006470)
- **Species:** Staphylococcus epidermidis (species) [taxon 1282], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12321588/full.md

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Source: https://tomesphere.com/paper/PMC12321588