# Autologous Blood Patch Pleurodesis for Persistent Pneumothorax in Emphysematous Lung: Salvage Success After Chemical Failure

## TL;DR

A high-risk patient with a persistent lung air leak was successfully treated with a blood-based procedure after chemical treatments failed.

## Contribution

Demonstrates autologous blood patch pleurodesis as a viable, non-surgical alternative for refractory pneumothorax in high-risk patients.

## Key findings

- Autologous blood patch pleurodesis resolved the air leak rapidly in a patient with emphysema.
- The procedure achieved complete lung re-expansion without the need for surgery.
- This case highlights the safety and potential of ABPP in patients with high operative risk.

## Abstract

Persistent air leaks (PALs) present a significant challenge in patients with underlying structural lung abnormalities, such as emphysema. Conventional interventions, including chemical pleurodesis, may be ineffective or poorly tolerated in this population. We present a case of a high-risk patient with refractory pneumothorax successfully managed with autologous blood patch pleurodesis (ABPP). This approach demonstrated rapid resolution of air leak and complete lung re-expansion without surgical intervention. The case underscores ABPP's potential as a safe, bedside alternative in selected patients, particularly those with incomplete pleural apposition or high operative risk.