# Research Progress of Combining High Tibial Osteotomy with Platelet-rich Plasma for Osteoarthritis Therapy

## TL;DR

This paper reviews combining high tibial osteotomy with platelet-rich plasma to treat knee osteoarthritis, showing potential benefits for pain and cartilage repair.

## Contribution

The novelty lies in combining platelet-rich plasma with high tibial osteotomy to enhance osteoarthritis treatment outcomes.

## Key findings

- Combined HTO and PRP therapy improves postoperative pain and function.
- PRP promotes cartilage repair and enhances bone cartilage structure.
- More research is needed to confirm the combined therapy's efficacy.

## Abstract

High tibial osteotomy (HTO) has been widely applied in clinical practice to treat unilateral knee osteoarthritis (OA). In order to improve the effectiveness of surgical treatment, researchers attempted to use a combination of platelet-rich plasma (PRP) and HTO therapy. We summarized the clinical outcomes of engaging HTO and PRP and found promising clinical advantages in improving postoperative pain and function, promoting cartilage repair, and increasing bone cartilage structure in patients. Further studies are needed to provide more convincing evidence of the efficacy of the combined therapy.