# Acute Adenoviral Gastroenteritis Complicated by Interstitial Edematous Pancreatitis in an Adult Patient: A Rare Clinical Case With a Multidisciplinary Approach

**Authors:** Anastasiia K Shkvarok, Yaroslava V Korost, Denys V Reizin, Yehor S Lisovenko

PMC · DOI: 10.7759/cureus.87328 · Cureus · 2025-07-05

## TL;DR

A rare case of adult adenoviral gastroenteritis complicated by pancreatitis is described, highlighting the unusual severity in an adult patient.

## Contribution

This paper presents a rare clinical case of adenoviral gastroenteritis complicated by pancreatitis in an adult, emphasizing the need for multidisciplinary care.

## Key findings

- Adenovirus F (type 40/41) caused acute gastroenteritis complicated by pancreatitis in a 24-year-old woman.
- The patient exhibited a pronounced intoxication syndrome, requiring a multidisciplinary approach for management.
- The case underscores the potential for severe complications from adenoviral infections in adults.

## Abstract

Adenovirus F (type 40/41) is one of the most significant viral etiological agents of acute gastroenteritis in young children. This is a significant and growing cause of pediatric gastroenteritis worldwide, particularly in children under the age of five. However, in rare cases, it may also lead to clinically significant illness in adults. The clinical case we present describes the course of acute adenoviral gastroenteritis complicated with acute pancreatitis and a pronounced intoxication syndrome in a 24-year-old woman from Ukraine.

## Linked entities

- **Diseases:** gastroenteritis (MONDO:0002269), pancreatitis (MONDO:0004982)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** watery diarrhea (MESH:D003969), respiratory tract infections (MESH:D012141), necrosis (MESH:D009336), hepatitis (MESH:D056486), viral gastroenteritis (MESH:D014777), vomiting (MESH:D014839), enteric infections (MESH:D004751), edema (MESH:D004487), fever (MESH:D005334), metabolic acidosis (MESH:D000138), conjunctivitis (MESH:D003231), Interstitial Edematous Pancreatitis (MESH:D010195), weakness (MESH:D018908), infectious disease (MESH:D003141), adenoviral infections (MESH:D007239), hypotension (MESH:D007022), inflammatory (MESH:D007249), abdominal tenderness (MESH:D000007), neutrophilia (MESH:C563010), cystitis (MESH:D003556), shigellosis (MESH:D004405), Adenoviral Gastroenteritis (MESH:D005759), gastrointestinal complications (MESH:D005767), interstitial nephritis (MESH:D009395), salmonellosis (MESH:D012480), diarrhea (MESH:D003967), nausea (MESH:D009325), hemorrhagic cystitis (MESH:D006470), dehydration (MESH:D003681), lymphopenia (MESH:D008231), acute intestinal infection (MESH:D000208), toxic syndrome (MESH:D064420), gastrointestinal symptoms (MESH:D012817), colitis (MESH:D003092), pseudocysts (MESH:D010192), adenovirus infection (MESH:D000257)
- **Chemicals:** ondansetron (MESH:D017294), hydrogen (MESH:D006859), metoclopramide (MESH:D008787), lactate (MESH:D019344), drotaverine (MESH:C005317), TCO2 (MESH:C561418), carbon dioxide (MESH:D002245), Glu (MESH:D018698), Na+ (MESH:D012964), pO2 (MESH:C093415), paracetamol (MESH:D000082), K+ (MESH:D011188), glucose (MESH:D005947), Ca++ (MESH:D002118), papaverine (MESH:D010208), oxygen (MESH:D010100), HCO3 (MESH:D001639), HCO3std (-)
- **Species:** Sapovirus (genus) [taxon 95341], Clostridioides difficile (species) [taxon 1496], Lactobacillus (genus) [taxon 1578], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Saccharomyces boulardii [taxon 252598], Campylobacter jejuni (species) [taxon 197], Shigella (genus) [taxon 620], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Rotavirus A (no rank) [taxon 28875], Escherichia coli O157 (serogroup) [taxon 1045010], Norovirus (genus) [taxon 142786], Ehrlichia sp. IE-C (species) [taxon 371764], Escherichia coli (E. coli, species) [taxon 562], Yersinia enterocolitica (species) [taxon 630], Salmonella (genus) [taxon 590], Bifidobacterium (genus) [taxon 1678], Homo sapiens (human, species) [taxon 9606], Campylobacter coli (species) [taxon 195], Adenoviridae (family) [taxon 10508]

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12320754/full.md

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Source: https://tomesphere.com/paper/PMC12320754