# A Rare Case of Takayasu Arteritis Presenting With Syncope and Elevated Inflammatory Markers in an Elderly Male With Learning Disability

**Authors:** Fayyas Ahamed, Mohamed Abdulmajeed, Ali Haider, Julee William, Kenneth Lee

PMC · DOI: 10.7759/cureus.87320 · Cureus · 2025-07-05

## TL;DR

An elderly man with a learning disability was diagnosed with rare Takayasu arteritis after showing symptoms like syncope and high inflammation markers.

## Contribution

Highlights the importance of considering large-vessel vasculitis in elderly patients and those with cognitive impairments.

## Key findings

- Takayasu arteritis was diagnosed in a 77-year-old male with learning disability.
- Imaging showed aortic and arch vessel thickening consistent with TAK.
- The patient responded well to corticosteroid treatment.

## Abstract

Takayasu arteritis (TAK) is a rare large-vessel vasculitis predominantly affecting young females. We present a unique case of a 77-year-old male with learning disability, presenting with constitutional symptoms, syncope, and elevated inflammatory markers. Imaging revealed circumferential thickening of the aorta and arch vessels, consistent with TAK. This case underscores the importance of considering large-vessel vasculitis even in elderly patients, as well as the diagnostic challenges in individuals with cognitive impairment. The patient responded well to corticosteroid therapy.

## Linked entities

- **Diseases:** Takayasu arteritis (MONDO:0017991), learning disability (MONDO:0004681)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, CD79A (CD79a molecule) [NCBI Gene 973] {aka IGA, IGAlpha, MB-1, MB1}
- **Diseases:** vision loss (MESH:D014786), empyema (MESH:D004653), jaw claudication (MESH:D007383), vomiting (MESH:D014839), Learning Disability (MESH:D007859), LVV (MESH:D014657), gastritis (MESH:D005756), infectious aortitis (MESH:D001025), cognitive decline (MESH:D003072), confusion (MESH:D003221), sepsis (MESH:D018805), fever (MESH:D005334), headache (MESH:D006261), autoimmune diseases (MESH:D001327), lymphoma (MESH:D008223), pneumonia (MESH:D011014), thrombocytosis (MESH:D013922), GCA (MESH:D013700), chest pain (MESH:D002637), arteritis (MESH:D001167), IgG4-related disease (MESH:D000077733), type 2 diabetes (MESH:D003924), pulse asymmetry (MESH:D005146), toxicity (MESH:D064420), granulomatous disease (MESH:D006105), inflammatory or infectious diseases (MESH:D003141), TIA (MESH:D002546), anemia (MESH:D000740), TAK (MESH:D013625), hypertension (MESH:D006973), Syncope (MESH:D013575), ischemia (MESH:D007511), dizziness (MESH:D004244), atelectasis (MESH:D001261), infection (MESH:D007239), stenosis (MESH:D003251), Inflammatory (MESH:D007249), fatigue (MESH:D005221), ischemic (MESH:D002545), aspiration (MESH:D011015), scalp tenderness (MESH:D063806), hyperglycemia (MESH:D006943), Coma (MESH:D003128), agitation (MESH:D011595), vascular damage (MESH:D057772), dry cough (MESH:D003371)
- **Chemicals:** piperacillin-tazobactam (MESH:D000077725), calcium (MESH:D002118), clarithromycin (MESH:D017291), oxygen (MESH:D010100), methotrexate (MESH:D008727), meropenem (MESH:D000077731), vitamin D (MESH:D014807), azathioprine (MESH:D001379), folate (MESH:D005492), tocilizumab (MESH:C502936), prednisolone (MESH:D011239), co-amoxiclav (MESH:D019980), blood glucose (MESH:D001786), steroid (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12319847/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12319847/full.md

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Source: https://tomesphere.com/paper/PMC12319847