# mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response

**Authors:** Loredana Urso, Irene Bertazzolo, Alberto Corradin, Micol Silic-Benussi, Sonia A. Minuzzo, Donna M. D’Agostino, Vincenzo Ciminale

PMC · DOI: 10.1038/s41392-025-02368-8 · Signal Transduction and Targeted Therapy · 2025-08-04

## Full-text entities

- **Genes:** MTOR (mechanistic target of rapamycin kinase) [NCBI Gene 2475] {aka FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS}
- **Diseases:** T-ALL (MESH:D054218)
- **Chemicals:** Venetoclax (MESH:C579720)

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Source: https://tomesphere.com/paper/PMC12319092