# A patient with acute hepatitis E and intractable vomiting: a case report

**Authors:** Kui Deng, Xiao-Qin Dong, Dong Xu

PMC · DOI: 10.3389/fmed.2025.1614921 · Frontiers in Medicine · 2025-07-21

## TL;DR

This case report describes a patient with acute hepatitis E who experienced unusual symptoms like intractable vomiting and dizziness.

## Contribution

The report highlights uncommon clinical manifestations of hepatitis E, adding to the understanding of its diverse symptomatology.

## Key findings

- The patient exhibited dizziness and vomiting, which are not typical for hepatitis E.
- Conservative treatment over a month led to significant improvement in symptoms.
- Follow-up showed good recovery, suggesting effective management of the condition.

## Abstract

We reported a patient with acute hepatitis E who had recurrent vomiting and dizziness that are uncommon in other patients with hepatitis E. The patient developed dizziness 1 month ago prior, accompanied by yellow urine, sclera, and staining of the skin. Half a month prior, the patient gradually developed fatigue and a poor appetite, accompanied by nausea, aversion to oil, loss of appetite, and itching of the skin. The patient turned out to have an acute hepatitis E infection and was hospitalized for more than a month with repeated vomiting and dizziness. He was treated conservatively with drugs for various reasons. After more than 1 month of medication and rest, the patient's vomiting and dizziness symptoms improved significantly, and follow-up found that the recovery was good.

## Full-text entities

- **Genes:** CALCA (calcitonin related polypeptide alpha) [NCBI Gene 796] {aka CALC1, CGRP, CGRP-I, CGRP-alpha, CGRP1, CT}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}, FAS (Fas cell surface death receptor) [NCBI Gene 355] {aka ALPS1A, APO-1, APT1, CD95, FAS1, FASTM}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}
- **Diseases:** edema (MESH:D004487), hemangioma (MESH:D006391), lesion (MESH:D009059), Vomiting (MESH:D014839), pancreatitis (MESH:D010195), intestinal obstruction (MESH:D007415), digestive tract obstruction (MESH:D004828), digestive tract diseases (MESH:D004066), constipation (MESH:D003248), itchy skin (MESH:D012871), fever (MESH:D005334), gastrointestinal bleeding (MESH:D006471), pancreatic diseases (MESH:D010182), Hyperbilirubinemia (MESH:D006932), effusion (MESH:D000080324), Blood coagulation (MESH:D001778), inflammation (MESH:D007249), tumors (MESH:D009369), Liver (MESH:D017093), Infection (MESH:D007239), chronic gastritis (MESH:D005756), itching of the skin (MESH:D011537), sepsis (MESH:D018805), viremia (MESH:D014766), autoimmune liver disease (MESH:D008107), hepatitis (MESH:D056486), brain atrophy (MESH:C566985), cyst (MESH:D003560), fossa (MESH:D015192), viral hepatitis (MESH:D014777), mucosa (MESH:D018442), bleeding (MESH:D006470), brachial neuritis (MESH:D020968), Guillain-Barre syndrome (MESH:D020275), jaundice (MESH:D007565), nausea (MESH:D009325), myelitis (MESH:D009187), deficiency of bile acids (MESH:C567652), car accident (MESH:C566176), vestibular dysfunction (MESH:D015837), intestinal metaplasia (MESH:D007410), cholestasis (MESH:D002779), Hepatitis E (MESH:D016751), loss of appetite (MESH:D001068), chronic (MESH:D002908), kidney (MESH:D007674), nausea and vomiting (MESH:D020250), atrophy (MESH:D001284), cholecystitis (MESH:D002764), Acute hepatitis E (MESH:D017114), digestive tract tumors (MESH:D004067), dizziness (MESH:D004244), abdominal pain (MESH:D015746), nystagmus (MESH:D009759), atrophic gastritis (MESH:D005757), deep venous thrombosis (MESH:D020246), mononeuritis multiplex (MESH:D020422), facial nerve palsy (MESH:D005155), gastrointestinal damage (MESH:D005767), meningitis (MESH:D008580)
- **Chemicals:** titanium (MESH:D014025), water (MESH:D014867), Polyene phosphatidylcholine (MESH:C029449), sodium phosphate (MESH:C018279), ribavirin (MESH:D012254), adrenalin (MESH:D004837), Levofloxacin (MESH:D064704), TBIL (MESH:D001663), cortisol (MESH:D006854), bile acid (MESH:D001647), Ursodeoxycholic acid (MESH:D014580), Adenosylmethionine (MESH:D012436), Biapenan (-), biapenem (MESH:C065257), Ceftazidime (MESH:D002442), glutathione (MESH:D005978)
- **Species:** hepatitis E virus [taxon 12461], human gammaherpesvirus 4 (Epstein Barr virus, no rank) [taxon 10376], Homo sapiens (human, species) [taxon 9606], Cytomegalovirus (genus) [taxon 10358]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12319049/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12319049/full.md

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Source: https://tomesphere.com/paper/PMC12319049