# The association between solid fuel use and oral health: the mediating effect of depressive symptom

**Authors:** Hui Jin, Ai-ping Deng, Hua Tian, Mao-Sheng Ran

PMC · DOI: 10.3389/froh.2025.1583685 · Frontiers in Oral Health · 2025-07-21

## TL;DR

Using solid fuel for cooking is linked to worse periodontal health, partly because it increases depressive symptoms.

## Contribution

This study identifies depressive symptoms as a mediator between solid fuel use and periodontal disease.

## Key findings

- Solid fuel use increases the risk of periodontal disease (OR: 1.35).
- Depressive symptoms mediate 7.89% of the link between solid fuel use and periodontal disease.

## Abstract

This study aimed to investigate the associations between solid fuel use and oral health and the mediating effects of depressive symptom.

64,521 Indian adults were included in this study. Binary logistic regression was performed to evaluate the associations of solid fuel use with tooth loss, dental cavity, and periodontal disease. Mediating analysis was used to investigate the effects of depressive symptom on the associations between solid fuel use and oral health.

Participants who claimed solid fuel use for cooking exhibited an increased risk of periodontal disease (OR: 1.35, 95% CI: 1.29–1.42) after adjusting for potential confounders. There were no significant associations of solid cooking fuel with tooth loss and dental caries. 7.89% of the relationship between solid fuel use and periodontal disease was mediated by depressive symptom.

The use of solid cooking fuel is associated with the increased prevalence of periodontal disease. Depressive symptom mediates the relationship between solid fuel use and periodontal disease. In the management of oral heath, the adverse impact of solid fuel use should be considered. Future studies should further clarify the mechanisms underlying the association between solid fuel and periodontal disease.

## Linked entities

- **Diseases:** periodontal disease (MONDO:0002635)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, NFE2L2 (NFE2 like bZIP transcription factor 2) [NCBI Gene 4780] {aka IMDDHH, NRF2, Nrf-2}
- **Diseases:** tooth loss (MESH:D016388), anemia (MESH:D000740), Depressive Symptom (MESH:D003866), Diseases (MESH:D004194), heart disease (MESH:D006331), oral disease (MESH:D009059), neuronal signaling abnormalities (MESH:C566796), physical (MESH:D059445), digestive cancer (MESH:D009369), inflammation (MESH:D007249), infection (MESH:D007239), HAP (MESH:D004618), lung disease (MESH:D008171), arthritis (MESH:D001168), ulcers (MESH:D014456), OS (MESH:D000079225), hypertension (MESH:D006973), caries (MESH:D003731), diabetes (MESH:D003920), thyroid disease (MESH:D013959), kidney disease (MESH:D007674), cognitive impairment (MESH:D003072), periodontitis (MESH:D010518), bleeding gums (MESH:C537732), Periodontal disease (MESH:D010510)
- **Chemicals:** ROS (MESH:D017382), CO (MESH:D002248), charcoal (MESH:D002606), NO2 (MESH:D009585), HAP (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12318992/full.md

## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12318992/full.md

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Source: https://tomesphere.com/paper/PMC12318992