# Laparoscopic Myomectomy and Pregnancy Outcomes: A Narrative Review

**Authors:** Vaia G Sarli, Aikaterini Lydia Vogiatzoglou, Theofanakis Charalampos, Dimos Sioutis, Periklis Panagopoulos, Nikolaos Machairiotis

PMC · DOI: 10.7759/cureus.87268 · Cureus · 2025-07-04

## TL;DR

Laparoscopic myomectomy is a safe and effective surgery for women with fibroids, improving pregnancy outcomes and preserving fertility.

## Contribution

This review evaluates laparoscopic myomectomy's effectiveness in improving fertility and pregnancy outcomes in women with fibroid-related infertility.

## Key findings

- Postoperative pregnancy rates after laparoscopic myomectomy ranged from 44% to 62%.
- Vaginal delivery was feasible in many cases, with rare complications like uterine rupture (<1%).
- Laparoscopic myomectomy proved effective even for multiple or large fibroids.

## Abstract

Uterine fibroids (leiomyomas) are common benign tumors in women of reproductive age and are often associated with infertility, heavy menstrual bleeding, and pelvic discomfort. Laparoscopic myomectomy (LSM) has emerged as a fertility-preserving alternative to open surgery, offering faster recovery and reduced perioperative morbidity. This review aims to evaluate the effectiveness of laparoscopic myomectomy in improving pregnancy outcomes among women with fibroid-related infertility. A literature review was conducted using PubMed and Web of Science to identify retrospective cohort studies, case reports, and systematic reviews assessing fertility outcomes after LSM. Data on patient demographics, fibroid characteristics, surgical technique, and reproductive outcomes were extracted and analyzed to assess trends in pregnancy rates, delivery methods, and complications. Fifteen retrospective cohort studies and one case report were included in the analysis. Postoperative pregnancy rates ranged from 44% to 62% across studies, with a high proportion of successful full-term deliveries. Vaginal delivery was feasible in many cases, and complications such as uterine rupture were rare (<1%). Proper suturing techniques and minimally invasive approaches contributed to favorable reproductive outcomes, with LSM proving to be effective even in cases of multiple or large fibroids. Laparoscopic myomectomy is a safe and effective surgical option for women seeking fertility preservation. The procedure is associated with high postoperative pregnancy and live birth rates, minimal complications, and promising obstetric outcomes. Continued advancements in laparoscopic techniques and further large-scale studies with long-term follow-up are needed to refine patient selection and optimize results.

## Full-text entities

- **Genes:** MED12 (mediator complex subunit 12) [NCBI Gene 9968] {aka ARC240, CAGH45, FGS1, HDKR, HOPA, Kto}
- **Diseases:** benign tumors (MESH:D009369), blood (MESH:D006402), abnormal uterine bleeding (MESH:D014592), adhesions (MESH:D000267), Uterine fibroids (MESH:D007889), smooth muscle tumors (MESH:D018235), OM (MESH:D005597), uterine rupture (MESH:D014597), ectopic pregnancies (MESH:D011271), reproductive dysfunction (MESH:D060737), endometriosis (MESH:D004715), infertility (MESH:D007246), miscarriage (MESH:D000022), postoperative pain (MESH:D010149), dysmenorrhea (MESH:D004412), miscarriage or rupture (MESH:D012421), abnormal placentation (MESH:D010922), abortions (MESH:D000026), bleeding (MESH:D006470), Uterine leiomyomas (OMIM:150699), blood loss (MESH:D016063)
- **Chemicals:** LSM (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12318358/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12318358/full.md

---
Source: https://tomesphere.com/paper/PMC12318358