# Angioleiomyoma of the Volar Aspect of the Right Small Finger: A Case Report

**Authors:** Sahil Dave, Suhirad Khokhar, Waqas Mahmud, Mohamed Alshal, John Diks

PMC · DOI: 10.7759/cureus.89165 · Cureus · 2025-07-31

## TL;DR

A rare case of angioleiomyoma in a finger is reported, highlighting the importance of tissue diagnosis for accurate identification and treatment.

## Contribution

This report adds to the limited literature on angioleiomyoma in the hand and underscores the need for histopathological confirmation.

## Key findings

- Angioleiomyoma was diagnosed via histopathology and immunohistochemistry showing desmin and CD34 markers.
- The case highlights the diagnostic challenges due to overlap with other benign lesions.
- Surgical excision is presented as an effective treatment for this condition.

## Abstract

A 53-year-old right-hand-dominant man presented with a recurrent, painful mass localized to the volar surface of the right small finger, leading to discomfort and impaired function. Radiographic imaging was unremarkable for osseous involvement. Surgical excision followed by histopathological and immunohistochemical (IHC) analysis established the diagnosis of angioleiomyoma, marked by desmin-positive smooth muscle fibers and CD34-positive vasculature. Given its infrequency in the hand and overlap with more common benign lesions, angioleiomyoma remains diagnostically elusive. This report emphasizes the pivotal role of tissue-based diagnostics and supports excision as a definitive treatment modality.

## Linked entities

- **Proteins:** LOC101066771 (desmin-like), CD34 (CD34 molecule)
- **Diseases:** angioleiomyoma (MONDO:0006646)

## Full-text entities

- **Genes:** CD34 (CD34 molecule) [NCBI Gene 947], DES (desmin) [NCBI Gene 1674] {aka CDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R}
- **Diseases:** painful (MESH:D010146), Angioleiomyoma (MESH:D018229)

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12317775/full.md

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Source: https://tomesphere.com/paper/PMC12317775