# Asymptomatic Pulmonary Embolus in a Patient With a Prior Heart Transplant

**Authors:** Addison Smartt, Diego Alegre, Jackie Kelley, James Kelley, Brennan Hand, Douglas Rappaport

PMC · DOI: 10.7759/cureus.87224 · Cureus · 2025-07-03

## TL;DR

A heart transplant patient developed an asymptomatic pulmonary embolism, emphasizing the need for vigilance in managing blood clots in such patients.

## Contribution

This case highlights the risk of asymptomatic pulmonary embolism in long-term heart transplant recipients.

## Key findings

- A 63-year-old heart transplant patient presented with an asymptomatic pulmonary embolism.
- The patient had an extensive deep vein thrombosis in the right lower extremity.
- Anticoagulation therapy successfully managed the condition without complications.

## Abstract

Heart transplant patients have a significant risk for both deep vein thrombosis (DVT) and pulmonary embolism (PE). This report presents a case of asymptomatic PE in a 63-year-old male patient with a history of orthotropic heart transplant nine years prior. The patient initially presented to the Emergency Department with acute right lower extremity pain and was found to have an extensive DVT involving the femoral vein and extending into the deep veins of the right calf. The patient was admitted to the transplant cardiology inpatient service, managed with a heparin infusion, and eventually transitioned to a direct oral anticoagulant with apixaban and discharged on hospital day 2 without further complications. This case highlights the importance of recognizing the heightened risk of venous thromboembolism in heart transplant patients at any point in their post-transplant course, despite the lack of classic symptoms of PE.

## Linked entities

- **Chemicals:** apixaban (PubChem CID 10182969)
- **Diseases:** pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Diseases:** pain (MESH:D010146), PE (MESH:D011655), Pulmonary Embolus (MESH:D004617), venous thromboembolism (MESH:D054556), DVT (MESH:D020246)
- **Chemicals:** heparin (MESH:D006493), apixaban (MESH:C522181)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12317595/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12317595/full.md

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Source: https://tomesphere.com/paper/PMC12317595