# Postoperative urinary stone analysis—influence of the hydrogel retrieval method on stone analysis

## TL;DR

This study examines how using hydrogel during urinary stone removal affects the accuracy of stone analysis, finding that proper washing preserves results.

## Contribution

The study demonstrates that hydrogel does not affect stone analysis when washed as recommended.

## Key findings

- Proper washing of stones after hydrogel treatment preserves accurate stone composition analysis.
- Failure to wash stones after hydrogel leads to undetermined stone composition due to interference.
- Stone analysis remains 100% consistent when manufacturer instructions are followed.

## Abstract

Stone analysis is crucial in patients with urolithiasis in order to initiate specific metaphylaxis in patients with high risk of recurrence. Hydrogel (mediNik®, Farco) was developed in order to improve stone-free rates. The aim of this study was to investigate whether the use of hydrogel influences the stone analysis.

This randomized prospective blinded study was based on a total of 78 urinary stone analyses, the composition of which was measured before and after treatment with hydrogel. Samples were washed according to the manufacturer’s instructions (group 1), with EDTA only (group 2) or not washed after treatment with hydrogel (group 3). The samples were analyzed using Fourier transform infrared spectroscopy (ATR technique).

In group 1 (100%, 63) and group 2 (100%, 5), the same urinary stone findings were recorded before and after application of the hydrogel. In group 3, the composition of none of the stones could be determined due to additional bands.

Postoperative urinary stone analysis using IR spectroscopy is not impaired by the hydrogel if the hydrogel is washed out as recommended by the manufacturer. After regular washing, the stone analysis remains the same in 100% of cases with and without the use of hydrogel.