# Management of Bleeding due to Idiopathic Colonic Varices

**Authors:** Abhimati Ravikulan, Richard Gearry, Jan Kubovy

PMC · DOI: 10.14309/crj.0000000000001791 · ACG Case Reports Journal · 2025-08-01

## TL;DR

A rare case of bleeding from unknown colon varices in a man without liver disease was successfully treated with endoscopic intervention and beta-blockers.

## Contribution

This case report presents a successful treatment approach for idiopathic colonic varices using endoscopic therapy and carvedilol.

## Key findings

- A 66-year-old man with idiopathic colonic varices was treated successfully with endoscopic intervention.
- Carvedilol was used as secondary prophylaxis for managing idiopathic colonic varices.
- The case highlights the potential role of nonselective beta-blockers in managing ICV despite unknown pathophysiology.

## Abstract

Lower gastrointestinal bleeding due to idiopathic colonic varices (ICV) is very rare. We present a 66-year-old man with recurrent hematochezia but without history of liver disease or portal hypertension. Colonoscopy revealed extensive varices throughout the colon. There was no biochemical or radiological evidence of cirrhosis or portal hypertension. The underlying etiology of ICV is unknown, and management of this condition is challenging without standardized treatment protocols. Nonselective beta-blockers could be considered despite the unknown ICV pathophysiology and their effect in this clinical entity. The successful management in our case included immediate endoscopic treatment and secondary prophylaxis with carvedilol.

## Linked entities

- **Chemicals:** carvedilol (PubChem CID 2585)
- **Diseases:** portal hypertension (MONDO:0005080), cirrhosis (MONDO:0005155)

## Full-text entities

- **Diseases:** cirrhosis (MESH:D005355), Lower gastrointestinal bleeding (MESH:D006471), liver disease (MESH:D008107), varices (MESH:D014648), portal hypertension (MESH:D006975), Bleeding (MESH:D006470), Colonic Varices (MESH:C565172)
- **Chemicals:** carvedilol (MESH:D000077261)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12316347/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12316347/full.md

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Source: https://tomesphere.com/paper/PMC12316347