# When to stop: Understanding the landscape of extreme-duration cardiopulmonary resuscitation practices among pediatricians in Sudan

**Authors:** Mohammed Abdulrahman Alhassan, Chiara Lazzeri, Chiara Lazzeri

PMC · DOI: 10.1371/journal.pone.0328704 · PLOS One · 2025-08-01

## TL;DR

This study explores how often and why pediatricians in Sudan use very long cardiopulmonary resuscitation (CPR) on children, highlighting a lack of clear guidelines for when to stop.

## Contribution

The study provides insights into CPR duration practices and decision-making among Sudanese pediatricians, emphasizing the need for standardized protocols.

## Key findings

- Over half of respondents reported encountering extreme-duration (>12 hours) CPR at least once.
- Most termination decisions were based on absence of a pulse and heartbeat, not brain death or specific time limits.
- Lack of clear protocols and ethical concerns were cited as major barriers to stopping CPR.

## Abstract

Pediatric cardiopulmonary resuscitation (CPR) is a life-saving intervention, but its effectiveness in extreme durations remains debated. This study aimed to explore the frequency and decision-making regarding prolonged CPR (PCPR) practices in hospitalized Sudanese children.

A web-based cross-sectional survey was conducted among pediatricians and pediatric trainees in Sudan. The survey investigated their experience with prolonged, ultra-prolonged, and extreme-duration CPR and factors influencing termination decisions.

Ninety-six Sudanese pediatricians and trainees responded to the survey, reporting varied experiences with prolonged CPR durations: over half (51%) and 81% of respondents reported encountering extreme-duration (> 12 hours) and ultra-prolonged (> 2 hours) CPR at least once, respectively. Around 5% and 1% reported to have encountered CPR durations of 48–72 hours and more than 72 hours, respectively, while 18% reported a 12–14-hour as their record high CPR duration. Four participants reported encountering extreme-duration (> 12 hours) CPR more than 15 times. Respondents most frequently (41%) cited the absence of a pulse and heartbeat as the primary factor for terminating CPR. A vast majority acknowledged ethical considerations (84%) and a lack of clear protocols (83%) as a barrier to terminating PCPR. Thematic analysis of an open question revealed a critical need for a standardized protocol addressing PCPR, enhanced CPR training, and better post-resuscitation support.

This study revealed a relatively high frequency of extended-duration CPR in Sudanese pediatric settings. Termination decisions focused on cardiac activity becoming clinically undetectable rather than brain death signs or specific cutoff CPR durations. The absence of a clear protocol on when to terminate CPR seems to contribute the most to this phenomenon. Further research on patient outcomes after prolonged CPR in this context is warranted.

## Full-text entities

- **Diseases:** cardiac compressions (MESH:D009408), death (MESH:D003643), cardiac dysrhythmia (MESH:D001145), CPR (MESH:D006323), Brain death (MESH:D001926), PCPR (MESH:D008133), Respiratory arrest (MESH:D012131)
- **Chemicals:** BMV (-), Oxygen (MESH:D010100), adrenaline (MESH:D004837)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12316234/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12316234/full.md

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Source: https://tomesphere.com/paper/PMC12316234