# From Pain to Paralysis: Shingles Crosses the Line

**Authors:** Mazhar Alam, Omar Shafey

PMC · DOI: 10.7759/cureus.87168 · Cureus · 2025-07-02

## TL;DR

An elderly woman developed arm weakness after a shingles outbreak, highlighting a rare but impactful complication of herpes zoster.

## Contribution

This case report highlights zoster-associated limb paresis (ZALP) as a rare complication of herpes zoster.

## Key findings

- Weakness in the upper limb occurred soon after a shingles rash appeared.
- PCR testing confirmed herpes zoster DNA in skin lesions.
- Antiviral treatment led to gradual improvement in the patient's condition.

## Abstract

We report a rare case of monoparesis due to herpes zoster infection in an 83-year-old female. Weakness in the woman’s upper limb started soon after the appearance of a vesiculo-papular rash over the left shoulder area extending down into the arm. Investigations were essentially normal apart from herpes zoster DNA being detected in PCR testing of a swab taken from the skin lesions. Imaging studies ruled out other possible causes of weakness like stroke and brachial plexus injury. The patient was commenced on antiviral treatment, which led to gradual improvement in the weakness. This is one of the lesser-known complications of herpes zoster, which can have a significant impact on quality of life. Also called zoster-associated limb paresis (ZALP), it can affect 0.5-5% of herpes zoster cases.

## Linked entities

- **Diseases:** herpes zoster (MONDO:0005609)

## Full-text entities

- **Diseases:** ZALP (MESH:D006562), monoparesis (MESH:D010291), Pain (MESH:D010146), vesiculo-papular rash (MESH:D005076), skin lesions (MESH:D012871), brachial plexus injury (MESH:D020516), stroke (MESH:D020521), Weakness (MESH:D018908)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12316075/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12316075/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12316075/full.md

---
Source: https://tomesphere.com/paper/PMC12316075