# Effects of 24 weeks of collagen supplementation in active adults: Impact on body composition, neuromuscular and cardiorespiratory fitness

**Authors:** Carlos Elvira Aranda, Roser De Castellar Sansó, Loreto Lledó Rico, Concepción Suárez Llorca, José Antonio Pérez Turpin

PMC · DOI: 10.5114/biolsport.2025.147017 · Biology of Sport · 2025-02-12

## TL;DR

This study found that collagen supplementation may improve muscle performance and reduce musculoskeletal discomfort in active adults over 24 weeks.

## Contribution

The novel contribution is evidence that collagen supplementation enhances neuromuscular fitness and reduces discomfort in active older adults.

## Key findings

- Collagen group showed significant improvements in counter-movement jump performance.
- 72.1% of collagen group reported improved musculoskeletal discomfort compared to 10.3% in the placebo group.
- Training alone improved physical condition in all participants regardless of supplementation.

## Abstract

The aim of this study was to analyze the effects of hydrolyzed collagen supplementation on body composition, neuromuscular fitness and cardiorespiratory fitness in active subjects undergoing a 24-week training program. A randomized, double-blind, placebo-controlled trial was conducted in 90 adults aged 45–65 with osteoarticular discomfort, including 45 men and 45 women. Participants received either 10g of hydrolyzed collagen enriched with minerals and vitamins (experimental group, EG), or a placebo (control group, CG), while following a twice-weekly training program. Physical performance was assessed through grip strength, squat jump (SJ), counter-movement jump (CMJ), and a cardiopulmonary exercise test. Biochemical and hematological analyses were also conducted. Significant improvements were observed in CMJ for the EG (p = 0.032), with men showing greater gains than women (p = 0.049). No significant differences were found in SJ between groups. After 24 weeks, 72.1% of the EG reported improved musculoskeletal discomfort, compared to only 10.3% of the CG. The study suggests that collagen supplementation may enhance muscle performance, likely by promoting connective tissue remodeling and increasing tendon elasticity. However, training alone improved overall physical condition in all participants.

## Full-text entities

- **Diseases:** musculoskeletal discomfort (MESH:D009140)
- **Chemicals:** minerals (MESH:D008903), hydrolyzed (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12314484/full.md

## References

84 references — full list in the complete paper: https://tomesphere.com/paper/PMC12314484/full.md

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Source: https://tomesphere.com/paper/PMC12314484