# Identifying Responders to Transcatheter Interventions for Secondary Mitral Regurgitation

**Authors:** Diane Rizkallah, Carl Ammoury, Elio Haroun, Joseph El Roumi, Ben Alencherry, Rhonda Miyasaka, Amar Krishnaswamy, Samir Kapadia, Serge Harb, Deborah Kwon

PMC · DOI: 10.1007/s11936-025-01095-1 · Current Treatment Options in Cardiovascular Medicine · 2025-07-31

## TL;DR

This paper reviews how imaging techniques can help identify patients who are likely to benefit from transcatheter treatments for secondary mitral regurgitation.

## Contribution

It emphasizes the role of multi-modality imaging in predicting treatment response and guiding clinical decisions for SMR patients.

## Key findings

- Multi-modality imaging is essential for predicting outcomes in transcatheter interventions for secondary mitral regurgitation.
- Echocardiographic, CT, and CMR imaging parameters are key predictors of treatment response and long-term outcomes.
- Imaging helps in risk stratification and shared decision making for high-risk patients.

## Abstract

This article offers a comprehensive review of the literature on imaging predictors of response to transcatheter interventions for secondary mitral regurgitation (SMR).

Recent advancements in percutaneous valve therapies have broadened treatment options for high-risk patients with SMR. While recent studies have demonstrated significant reduction in all-cause mortality and hospitalizations with transcatheter edge-to-edge repair (TEER), significant controversy remains. This review highlights the central role of multi-modality imaging to guide therapeutic decision making for optimal treatment response and long-term outcomes.

Several echocardiographic, computerized tomography (CT) and cardiac magnetic resonance (CMR) imaging parameters are central to identifying optimal conditions for transcatheter therapies. Imaging features have become key predictors of outcomes following transcatheter interventions for secondary mitral regurgitation and provide important risk stratification to guide therapeutic decision making and shared decision making.

## Full-text entities

- **Diseases:** Mitral Regurgitation (MESH:D008944)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12313785/full.md

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Source: https://tomesphere.com/paper/PMC12313785