# Prognostic ability of the sTarT back screening tool for disability and pain intensity outcomes in older adults with low back pain seeking chiropractic care: a multi-national external validation study

**Authors:** Yanyan Fu, Alan D. Jenks, Sidney M. Rubinstein, Katie de Luca, Iben Axen, Bart W. Koes, Alessandro Chiarotto

PMC · DOI: 10.1186/s12998-025-00592-1 · Chiropractic & Manual Therapies · 2025-07-30

## TL;DR

This study tested a tool for predicting recovery from back pain in older adults visiting chiropractors but found it ineffective.

## Contribution

First multi-national validation of the SBT in older adults receiving chiropractic care for low back pain.

## Key findings

- The SBT showed poor discrimination for predicting no improvement in disability and pain intensity.
- AUC values were below 0.60 regardless of risk subgroup or sum score usage.
- Subgroup and sensitivity analyses did not improve the tool's predictive accuracy.

## Abstract

Low back pain (LBP) is common among older adults, and it is a frequent reason for seeking chiropractic care. The STarT Back Screening Tool (SBT) was developed to stratify patients with LBP into low, medium, and high-risk treatment pathways, so that the treatment can be matched to each participant’s risk profile. But its prognostic performance varies across settings and populations. No studies have focused on the SBT’s utility as a stratified-care tool in older adults with LBP in a chiropractic setting. Therefore, our aim was to evaluate the ability of the SBT to predict three-, six-, and 12-month disability and pain outcomes in older adults (≥55 years) with a new episode of LBP consulting chiropractors in the Netherlands, Sweden, and Australia.

This was a secondary analysis of the Back Complaints in Older Adults – Chiropractic (BACE-C) cohort. Participants visiting chiropractors with LBP completed baseline questionnaires for demographic and clinical characteristics, including the SBT. Follow-up questionnaires assessed disability (Roland Morris Disability Questionnaire (RMDQ)) and pain intensity (11-point Numerical Rating Scale (NRS)). “No improvement” on disability and pain intensity was defined as less than 30% reduction in baseline scores. We used logistic regression models to estimate discrimination metrics including the area under the receiver operating characteristic curve (AUC). Subgroup analyses were conducted by country, sex, and LBP duration; sensitivity analyses employed alternative “no improvement” definitions and linear regression on continuous outcome scores.

A total of 738 participants were included. The mean age of the study sample was 66.2 ± 7.5 years and 50.9% of the participants were female. The SBT showed poor discrimination for predicting no improvement in disability and pain intensity. All AUC values were below 0.60 regardless of whether SBT risk subgroups (i.e. low/medium/high) or the SBT sum score were used. Subgroup and sensitivity analyses did not meaningfully improve discrimination.

The SBT presented limited prognostic ability to predict outcomes of disability and pain intensity in older adults with LBP in a chiropractic setting. These findings suggest insufficient evidence for the prognostic ability of the SBT risk stratification tool. Future research should explore reasons behind the limited prognostic accuracy and consider potential modifications or alternative tools.

The online version contains supplementary material available at 10.1186/s12998-025-00592-1.

## Full-text entities

- **Genes:** SPNS1 (SPNS lysolipid transporter 1, lysophospholipid) [NCBI Gene 83985] {aka HSpin1, LAT, PP2030, SLC62A1, SLC63A1, SPIN1}
- **Diseases:** cognitive disorders (MESH:D003072), Disability (MESH:D009069), fracture (MESH:D050723), SBT (MESH:D020922), pelvic pain (MESH:D017699), persistent disability (MESH:D000088562), Back Complaints (MESH:D019567), Musculoskeletal Pain (MESH:D059352), LBP (MESH:D017116), infection (MESH:D007239), tumor (MESH:D009369), Pain (MESH:D010146), back pain (MESH:D001416), anxiety (MESH:D001007), depression (MESH:D003866)
- **Chemicals:** NO (MESH:D009614), RMDQ (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** -C — Mus musculus (Mouse), Finite cell line (CVCL_S361)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12312513/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12312513/full.md

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Source: https://tomesphere.com/paper/PMC12312513