# Patient experience of head and neck treatment on a 1.5 T MR-Linac: is the ATS-lite adaptive solution tolerable?

**Authors:** Helen Barnes, Sophie Alexander, Shreerang Bhide, Alex Dunlop, Amit Gupta, Kevin Harrington, Trina Herbert, Kee Howe Wong, Helen McNair

PMC · DOI: 10.1016/j.tipsro.2025.100324 · Technical Innovations & Patient Support in Radiation Oncology · 2025-07-21

## TL;DR

Patients undergoing head and neck cancer treatment on an MR-Linac report a positive experience with the ATS-lite adaptive radiotherapy method.

## Contribution

Demonstrates that MRI-guided adaptive radiotherapy for head and neck cancer does not negatively affect patient experience.

## Key findings

- ATS-lite treatment times averaged 39 minutes with 98.8% of sessions under 60 minutes.
- 96% of patient responses indicated positive experience on a Likert scale.
- Only 7 out of 46 backup plan uses were due to patient tolerance issues.

## Abstract

•Investigating patient tolerance is paramount when implementing new radiotherapy techniques.•Patient reported experience of head and neck treatment on the MR-Linac is positive.•MRI guided adaptive radiotherapy for HN cancer does not negatively impact the patient experience.

Investigating patient tolerance is paramount when implementing new radiotherapy techniques.

Patient reported experience of head and neck treatment on the MR-Linac is positive.

MRI guided adaptive radiotherapy for HN cancer does not negatively impact the patient experience.

Head and neck cancer (HNC) treatment on the Unity MR-Linac (MRL) (Elekta AB, Stockholm, Sweden) has been developed using the novel adapt-to-shape Lite (ATS-lite) method to create clinically acceptable adaptive treatments clinician-free. Here we investigate patient experience and acceptability of this technique.

Ten HNC patients treated to 65 Gy in 30 fractions with MRI-guided adaptive radiotherapy (MRIgART) within the PERMIT trial (NCT03727698), were included. Data collected comprised patient demographics, treatment time, and patient experience, using an established MRL questionnaire.

Back-up plans were created for use on the conventional linac with CT guidance, to prevent missed fractions. The frequency of use was collected and categorised to reflect the cause.

The median total treatment time for ATS-lite method was 39 min. The percentage of treatments under 60 mins was 98.8 %.

Questionnaire response rate was 85% and individual question response rate was 99%. Ninety-six percent of responses scored 2 or 3 on the Likert scale, a positive answer. The lowest scoring question was “I forced myself to manage the situation,” with a mean (SD) of 2.4 (0.9).

The MRL delivered 84.7 % of treatments. The back-up plan was used for 46 fractions, 7 attributed to patient tolerance (n = 2 patients).

Average treatment times for the ATS-lite HNC MRIgART are acceptable and faster than reported ATP treatment times. Patient-reported experience was extremely positive. Use of back-up plans attributable to lack of patient tolerance was low. This technique can used with the confidence that patient experience is not negatively impacted.

## Linked entities

- **Diseases:** head and neck cancer (MONDO:0005627)

## Full-text entities

- **Genes:** CDKN2A (cyclin dependent kinase inhibitor 2A) [NCBI Gene 1029] {aka ARF, CAI2, CDK4I, CDKN2, CMM2, INK4}
- **Diseases:** anxiety (MESH:D001007), disease (MESH:D004194), pain (MESH:D010146), weight loss (MESH:D015431), metallic (MESH:D013651), Cancer (MESH:D009369), panic attacks (MESH:D016584), HNC (MESH:D006258), squamous cell carcinomas (MESH:D002294), dizziness (MESH:D004244), toxicity (MESH:D064420)
- **Chemicals:** ATP (-), ATP (MESH:D000255)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12312102/full.md

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Source: https://tomesphere.com/paper/PMC12312102