# Anatomy, biomechanics, and clinical advances of proximal tibiofibular joint in pain management

**Authors:** Tianjun Zhai, Fengyan Jiang, Wei Feng, Zhaohui Chen

PMC · DOI: 10.3389/fsurg.2025.1604538 · Frontiers in Surgery · 2025-07-17

## TL;DR

This paper reviews the anatomy and clinical importance of the proximal tibiofibular joint in managing pain and mobility issues.

## Contribution

The paper highlights novel therapies like proximal fibular osteotomy for treating knee osteoarthritis.

## Key findings

- Dysfunction of the PTFJ can lead to pain and nerve compression.
- Proximal fibular osteotomy shows promise in treating medial compartment knee osteoarthritis.
- Multimodal imaging is essential for accurate diagnosis of PTFJ pathology.

## Abstract

This article presents a descriptive review focused on the proximal tibiofibular joint (PTFJ), a synovial plane joint located posterolaterally beneath the lateral tibial plateau. The PTFJ facilitates axial load transmission, allows subtle tibiofibular motion, and works in conjunction with the distal syndesmosis to preserve ankle and knee function. Dysfunction—resulting from anatomical variation, trauma, instability, or degeneration—can lead to pain, mobility impairment, and nerve compression. Clinical conditions such as osteoarthritis and peroneal nerve entrapment are increasingly linked to PTFJ pathology. Novel therapies like proximal fibular osteotomy (PFO) have shown promise in treating medial compartment knee osteoarthritis based on the uneven settling theory. Diagnosis involves multimodal imaging, and management spans conservative, interventional, and surgical approaches. A comprehensive understanding of the PTFJ supports accurate diagnosis and the development of effective treatment strategies.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** medial compartment knee osteoarthritis (MESH:D020370), trauma (MESH:D014947), mobility impairment (MESH:D014086), nerve compression (MESH:D009408), Dysfunction (MESH:D006331), peroneal nerve entrapment (MESH:D020427), pain (MESH:D010146), osteoarthritis (MESH:D010003)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12311852/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12311852/full.md

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Source: https://tomesphere.com/paper/PMC12311852