# Rehabilitation Interventions in Adults with Amyotrophic Lateral Sclerosis: A Review: -

**Authors:** Maryam Behroozinia, Saeid Khosrawi

PMC · DOI: 10.31661/gmj.vi.3708 · Galen Medical Journal · 2025-07-02

## TL;DR

This review explores how rehabilitation helps adults with ALS manage symptoms and improve quality of life in the absence of a cure.

## Contribution

The paper provides a comprehensive overview of multidisciplinary rehabilitation strategies tailored for ALS patients.

## Key findings

- Rehabilitation is critical for managing motor impairments and enhancing independence in ALS patients.
- Multidisciplinary care involving physical, occupational, and speech therapies is recommended to reduce disease impact.
- Rehabilitation strategies aim to improve functional abilities and quality of life while minimizing complications.

## Abstract

Amyotrophic Lateral Sclerosis (ALS) is the most common and rapidly devastating
neurodegenerative disease, which causes impairment of motor neurons in the upper
and lower limbs, as well as in the bulbar muscles among adults. This leads to
progressive weakness of voluntary muscles. The median survival after the
emergence of initial symptoms is typically three years. During this period, due
to the worsening of general well-being and independence, patients and their
caregivers experience significant emotional stress. Furthermore, there is
currently no definitive treatment for ALS. Consequently, patients face various
challenges associated with motor impairment, including mobility disturbances,
respiratory dysfunction, speech difficulties, and limitations in activities of
daily living. Therefore, rehabilitation plays a vital role as a component of
multidisciplinary care for managing these issues and reducing the impact of the
disease on patients and their families. It is considered the optimal choice for
alleviating the discomfort of ALS patients until a curative treatment is
discovered.This narrative review aims to provide an overview of different
aspects of rehabilitation, including physical therapy, occupational therapy,
speech therapy, and respiratory strategies focused on enhancing independence,
functional abilities, and overall quality of life while minimizing disabilities
and complications in patients coping with this debilitating condition.

## Linked entities

- **Diseases:** Amyotrophic Lateral Sclerosis (MONDO:0004976)

## Full-text entities

- **Diseases:** speech difficulties (MESH:D013064), ALS (MESH:D000690), motor impairment (MESH:D000068079), impairment of motor neurons (MESH:D016472), weakness of voluntary muscles (MESH:D018908), mobility disturbances (MESH:D014086), respiratory dysfunction (MESH:D012131), neurodegenerative disease (MESH:D019636)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

147 references — full list in the complete paper: https://tomesphere.com/paper/PMC12311630/full.md

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Source: https://tomesphere.com/paper/PMC12311630