# Characterization of Atherosclerotic Plaque in Coronary CT Angiography and Some Related Factors in Patients with Coronary Artery Disease Referred to Farshchian Heart Hospital in Hamadan in 2023: -

## TL;DR

This study examines atherosclerotic plaque characteristics in coronary artery disease patients and their links to risk factors like diabetes and hypertension.

## Contribution

The study identifies specific plaque patterns and their associations with demographic and clinical risk factors in coronary artery disease patients.

## Key findings

- 40% of patients had coronary artery stenosis, with 18% having severe stenosis.
- Low Attenuation plaque was associated with hypertension, diabetes, and dyslipidemia.
- Napkin-ring Sign was linked to diabetes.

## Abstract

Vascular classification in coronary artery disease is influenced by
atherosclerotic plaque characteristics. This study aimed to investigate the
characterization of atherosclerotic plaque and some related factors in
coronary
CT angiography in patients with coronary artery disease referred to
Farshchian
Heart Hospital in Hamadan in 2023

In this analytical
cross-sectional study that was conducted in 2023 in Hamadan, Iran, 140
individuals suspected of coronary artery stenosis based on atherosclerotic
plaque characteristics in coronary angiography were examined. The study
analyzed
the relationship between plaque features, demographic characteristics,
degree of
coronary artery stenosis, and other risk factors for coronary artery disease
with chi-square, logistic regression, correlation coefficient using SPSS
version
20.

The mean age of patients was 53.11±7.62 years, with 59% male and 40%
female. Among patients, 40% had coronary artery stenosis, with 18% having
severe
stenosis. The prevalence of positive remodeling was 32%, Low Attenuation was
45%, Napkin-ring Sign was 14%, and Spotty Calcium was 25%. Significant
associations were found between various plaque patterns and age (P0.05), Low
Attenuation pattern with hypertension (P0.001), diabetes (P=0.03),
dyslipidemia
(P=0.04), Napkin-ring Sign with diabetes (P=0.03).

The study
highlights the high prevalence of distinct plaque patterns and their
associations with severity of coronary artery stenosis, presence of
diabetes,
hypertension, and dyslipidemia. These findings emphasize the need for
tailored
risk assessment and management strategies in patients with coronary artery
disease.