# Ferumoxytol-enhanced magnetic resonance angiography for endovascular aortic repair surveillance in a patient after renal transplant

**Authors:** Richard Longfei Li, Daniel R. Ludwig, Anup S. Shetty, Vincent Mellnick, Brian G. Rubin

PMC · DOI: 10.1016/j.jvscit.2025.101898 · Journal of Vascular Surgery Cases, Innovations and Techniques · 2025-06-26

## TL;DR

A patient with a failing kidney transplant underwent a safer MRI scan using ferumoxytol to monitor a large aortic aneurysm.

## Contribution

Demonstrates the use of ferumoxytol-enhanced MRI as a safe alternative for imaging in patients with renal impairment.

## Key findings

- Ferumoxytol-enhanced MRI provided high-quality imaging for endoleak detection.
- Avoided iodinated and gadolinium-based contrast agents in a patient with renal issues.

## Abstract

Endovascular aneurysm repair requires lifelong imaging surveillance, typically with contrast-enhanced computed tomography imaging. This poses risks to patients with end-stage renal disease. Ferumoxytol, a superparamagnetic iron-based nanoparticle with minimal nephrotoxicity, has emerged as an alternative contrast agent for magnetic resonance angiography in patients with renal impairment. We present a case of a patient with a failing renal transplant who underwent ferumoxytol-enhanced magnetic resonance angiography to further characterize an indeterminant etiology of continued aneurysm sac expansion to 10 cm, avoiding iodinated and gadolinium-based contrast while achieving high-quality imaging for endoleak detection.

## Linked entities

- **Chemicals:** ferumoxytol (PubChem CID 6432052)
- **Diseases:** end-stage renal disease (MONDO:0004375)

## Full-text entities

- **Diseases:** endoleak (MESH:D057867), renal insufficiency (MESH:D051437), ESRD (MESH:D007676), compromised renal function (MESH:D058186), AAA (MESH:D017544), hypersensitivity (MESH:D004342), aneurysm (MESH:D000783), anaphylaxis (MESH:D000707), iron deficiency anemia (MESH:D018798), nephropathy (MESH:D007674), NSF (MESH:D054989), coronary artery disease (MESH:D003324)
- **Chemicals:** iron oxide (MESH:C000499), ferumoxtyol (-), gadolinium (MESH:D005682), Fe (MESH:D007501), Feraheme (MESH:D052203)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12311432/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12311432/full.md

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Source: https://tomesphere.com/paper/PMC12311432