# A Rare Case of Dextrocardia With Atrioventricular Septal Defect and Situs Inversus in an 8‐Month‐Old Infant Complicated by Severe Acute Malnutrition

**Authors:** Michael Tesfaye Kassa, Nuru Mohamed Ahmed, Mohamed Abdirahman Shukri, Fatumo Mohamed Abdikadir

PMC · DOI: 10.1002/ccr3.70604 · Clinical Case Reports · 2025-07-30

## TL;DR

This case report describes a rare combination of heart and body positioning defects in an Ethiopian infant with severe malnutrition.

## Contribution

The novelty lies in documenting the rare coexistence of situs inversus, dextrocardia, AV septal defect, and severe malnutrition in a single patient.

## Key findings

- The infant presented with situs inversus totalis, dextrocardia, and atrioventricular septal defect.
- Severe acute malnutrition complicated the clinical management in a resource-limited setting.
- Early surgical referral is emphasized to improve outcomes in such complex cases.

## Abstract

The key clinical message in this case report highlights the rare coexistence of situs inversus totalis, dextrocardia, atrioventricular septal defect, and severe acute malnutrition in an Ethiopian infant. It underscores the need for heightened awareness, timely diagnosis, and integrated management strategies for such complex congenital and nutritional disorders and emphasizes the need for early surgical referral in resource‐limited settings, as delayed intervention worsens outcomes.

## Linked entities

- **Diseases:** atrioventricular septal defect (MONDO:0020290)

## Full-text entities

- **Diseases:** deficient atrioventricular septation (MESH:D000093665), cyanotic lesion (MESH:D009059), cardiac anomalies (MESH:D006331), vomiting (MESH:D014839), cardiomegaly (MESH:D006332), infection (MESH:D007239), transposition of the great vessels (MESH:D014188), pathology (MESH:D005598), cardiorespiratory distress (MESH:D012128), atrial or ventricular septal defect (MESH:D006345), visceral misalignment disorder (MESH:D017760), loss of body mass (MESH:C536030), CHD (MESH:D006330), pulmonary tuberculosis (MESH:D014397), Acute malnutrition (MESH:D000067011), Dextrocardia (MESH:D003914), cough (MESH:D003371), persistent atrioventricular canal (MESH:D004694), congenital abnormality (MESH:D000013), hypoxia (MESH:D000860), situs (MESH:D002278), AVSD (MESH:C562831), congenital and nutritional disorders (MESH:D009748), gain (MESH:D015430), Situs ambiguus (MESH:D059446), Down syndrome (MESH:D004314), laterality defects (MESH:C563391), holosystolic murmur (MESH:D006337), congestive heart failure (MESH:D006333), Malnutrition (MESH:D044342), ostium primum atrial septal defect (MESH:D006344), Inversus (MESH:D012857), diarrhea (MESH:D003967), reduced (MESH:D001523)
- **Chemicals:** oxygen (MESH:D010100), ampicillin (MESH:D000667), Lasix (MESH:D005665), F-75 (-), gentamycin (MESH:D005839), spironolactone (MESH:D013148)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12311224/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12311224/full.md

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Source: https://tomesphere.com/paper/PMC12311224