# Value of three-dimensional imaging in tricuspid valve stenosis: a case series

**Authors:** Mahmoud Abdelnabi, Abdallah Almaghraby, Ramzi Ibrahim, Hoda Abdelgawad

PMC · DOI: 10.1186/s43044-025-00672-w · The Egyptian Heart Journal · 2025-07-30

## TL;DR

This case series shows that 3D echocardiography improves the diagnosis of tricuspid valve stenosis compared to 2D methods.

## Contribution

The study highlights the added value of 3DE in identifying key features of tricuspid valve stenosis.

## Key findings

- 2D echocardiography has limitations in diagnosing tricuspid valve stenosis.
- 3D echocardiography provides clear visualization of commissural fusion and chordal thickening.
- 3DE enables accurate tracing of the orifice area regardless of regurgitation.

## Abstract

Rheumatic tricuspid stenosis (TS) is a rare and easily missed clinical finding until late stages. Two-dimensional echocardiography (2DE) can assess the leaflet thickening and transvalvular gradients, which may be misleading in the presence of significant TR. Moreover, it lacks en face views of the tricuspid valve (TV), making the diagnosis of TS challenging. Meanwhile, three-dimensional echocardiography (3DE) effectively visualizes commissural fusion and sub-valvular thickening, enabling accurate tracing of the orifice area.

The authors present a case series discussing rheumatic and non-rheumatic TV stenosis to emphasize the role of 3DE in identifying the key findings in rheumatic stenotic TV and distinguishing them from other non-rheumatic etiologies.

This case series demonstrated that 2DE has limitations in diagnosing TV stenosis, whereas 3DE provides a clear view of features such as commissural fusion and chordal thickening. Therefore, 3DE is essential in addition to 2DE for improved imaging of TV diseases, allowing accurate tracing of the orifice area, regardless of regurgitation.

The online version contains supplementary material available at 10.1186/s43044-025-00672-w.

## Linked entities

- **Diseases:** tricuspid valve stenosis (MONDO:0005997)

## Full-text entities

- **Genes:** F2R (coagulation factor II thrombin receptor) [NCBI Gene 2149] {aka CF2R, HTR, PAR-1, PAR1, TR}
- **Diseases:** Tricuspid regurgitation (MESH:D014262), shortness of breath (MESH:D004417), rheumatic mitral and aortic valves (MESH:D008946), mitral regurgitation (MESH:D008944), murmur (MESH:D006337), carcinoid heart (MESH:D002275), Rheumatic tricuspid stenosis (MESH:D014264), diarrhea (MESH:D003967), wheezing (MESH:D012135), stenosis (MESH:D003251), rheumatic fever (MESH:D012213), lower limb swelling (MESH:D038061), systole (MESH:D000092244), aortic stenosis (MESH:D001024), carcinoid (MESH:D002276), swelling (MESH:D004487), valve diseases (MESH:D006349), atrial fibrillation (MESH:D001281), Rheumatic (MESH:D012216), aortic regurgitation (MESH:D001022)
- **Chemicals:** warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12311065/full.md

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Source: https://tomesphere.com/paper/PMC12311065