# Retroperitoneal invasive fibromatosis after laparoscopic radical resection of colon cancer: a case report and literature review

**Authors:** Tiantian Shan, Yiqi Zhang, Yang Yao, Min Li, Xiaoying Li

PMC · DOI: 10.3389/fonc.2025.1582253 · Frontiers in Oncology · 2025-07-17

## TL;DR

A rare case of retroperitoneal invasive fibromatosis occurring after colon cancer surgery is reported and reviewed.

## Contribution

This case report adds to the limited literature on postoperative retroperitoneal invasive fibromatosis in colorectal cancer patients.

## Key findings

- A 63-year-old male developed retroperitoneal invasive fibromatosis one year after colon cancer surgery.
- Diagnosis was confirmed using enhanced CT, pathological examination, and Whole Exome Sequencing.
- The case highlights the need for awareness of this rare condition in postoperative colorectal cancer patients.

## Abstract

Invasive fibromatosis is a rare, locally invasive, benign fibrous tumor that mainly occurs in the anterior abdominal wall and limbs, with a lower incidence in the retroperitoneum. This article reports a case of retroperitoneal invasive fibromatosis in a 63-year-old male patient. The patient underwent resection for sigmoid colon cancer and was diagnosed with retroperitoneal invasive fibromatosis through enhanced CT, pathological examination and Whole Exome Sequencing one year after surgery. Given the rarity of postoperative surgery-related retroperitoneal invasive fibromatosis in patients with colorectal cancer, this article aims to provide a reference for clinical research on retroperitoneal invasive fibromatosis by reporting this case.

## Linked entities

- **Diseases:** colon cancer (MONDO:0002032), colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** colon cancer (MESH:D015179), sigmoid colon cancer (MESH:D012811), Invasive fibromatosis (MESH:D005350), benign fibrous tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12310913/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12310913/full.md

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Source: https://tomesphere.com/paper/PMC12310913