# Comparison of postoperative outcomes following endoscopic third ventriculostomy or shunt in a propensity score matched pediatric cohort

**Authors:** Paulo Castro, Loren Berman, Joseph Piatt

PMC · DOI: 10.1007/s00381-025-06886-2 · Child's Nervous System · 2025-07-31

## TL;DR

This study compares outcomes of two hydrocephalus treatments in children and finds that younger patients have more complications with one procedure.

## Contribution

The study provides age-specific insights into postoperative outcomes of ETV versus shunt surgery in pediatric hydrocephalus patients.

## Key findings

- ETV in infants ≤6 months had higher rates of seizures, readmission, and reintervention compared to shunts.
- ETV in older children (≥2 years) showed shorter hospital stays and lower mortality than shunts.
- Short-term outcomes suggest ETV may be less favorable for younger patients despite long-term benefits.

## Abstract

Thirty-day readmission and reoperation are widely used quality metrics. Endoscopic third ventriculostomy (ETV) is favored when feasible, but may compare unfavorably with shunt in the short-term. This study analyzes 30-day outcomes of ETV and shunt surgery in comparable populations.

Data regarding patients undergoing ETV or initial shunt insertion were extracted from the National Surgical Quality Improvement Program – Pediatric for 2013–2020. Patients were stratified into three age groups: ≤ 6 months (N = 5,906), 6 months-2 years (N = 2,364), and ≥ 2 years (N = 4,408). Characteristics were compared before and after propensity-score matching. Outcome comparisons included CNS complications, mortality, readmission, and reinterventions.

There were 10,135 shunt insertions and 2,543 ETVs. After matching, patients ≤ 6 months undergoing ETV had more seizures (ETV 6.3% vs shunt 0.4%, p < 0.001), readmission (ETV 15.7% vs shunt 6.1%, p < 0.001), and reintervention (ETV 17.4% vs shunt 4.8%, p < 0.001). Among patients 6 months—2 years, ETV increased seizures (ETV 3.3% vs shunt 1.0%, p = 0.01), readmission (ETV 14.9% vs shunt 7.8%, p < 0.001), and reintervention (ETV 13.0% vs shunt 5.4%, p < 0.001). Among older patients, ETV had decreased median length of stay (ETV 3 days, IQR 1–6 days vs shunt 3 days, IQR 2–8 days, p = 0.0019) and mortality (ETV 0.4% vs shunt 1.5%, p = 0.007).

Outcomes following shunt surgery and ETV in matched patients appear to be age-dependent. Younger patients undergoing ETV encountered more short-term complications. 30-day outcomes may be misleading as a quality measure in the management of childhood hydrocephalus.

## Linked entities

- **Diseases:** hydrocephalus (MONDO:0001150)

## Full-text entities

- **Diseases:** Hydrocephalus (MESH:D006849), dehiscence (MESH:D013529), seizure disorder (MESH:D004827), hematologic disorder (MESH:D006402), Infection (MESH:D007239), renal insufficiency (MESH:D051437), seizure (MESH:D012640), ventricular tachycardia (MESH:D017180), nerve injury (MESH:D000080902), CNS abnormality (MESH:D002493), malignancy (MESH:D009369), neuromuscular disorder (MESH:D009468), coma (MESH:D003128), prematurity (MESH:C536271), spina bifida (MESH:D016135), developmental delay (MESH:D002658), stroke (MESH:D020521), acute renal failure (MESH:D058186), septic shock (MESH:D012772), congenital malformation (OMIM:163000), urinary tract infection (MESH:D014552), Systemic Inflammatory Response Syndrome (MESH:D018746), death (MESH:D003643), sepsis (MESH:D018805), pneumonia (MESH:D011014), cardiac arrest (MESH:D006323), SSI (MESH:D013530), cerebral palsy (MESH:D002547), IVH (MESH:D000074042)
- **Chemicals:** steroid (MESH:D013256), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12310776/full.md

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Source: https://tomesphere.com/paper/PMC12310776