# A patient with a purple, edematous great toe **Authors:** Hannah Bulosan, Yadira Castaneda Nunez, Bicong Wu, Evan George, Anna L. Cogen PMC · DOI: 10.1016/j.jdcr.2025.04.044 · JAAD Case Reports · 2025-06-16 ## Full-text entities - **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F} - **Diseases:** vasculitis (MESH:D014657), pseudogout (MESH:D002805), inflammatory arthritis (MESH:D001168), rheumatoid arthritis (MESH:D001172), ulcers (MESH:D014456), myositis ossificans (MESH:D009221), osteosarcoma (MESH:D012516), nail dystrophy (MESH:D009260), calcification (MESH:D002114), purpura (MESH:D011693), toe (MESH:D000070592), thrombosis (MESH:D013927), hemorrhagic (MESH:D006470), Raynaud (MESH:D011928), infarction (MESH:D007238), pulmonary sarcoidosis (MESH:D017565), Sarcoid dactylitis (MESH:D012507), bone erosions (MESH:D014077), bone lesions (MESH:D001847), musculoskeletal involvement (MESH:D009140), osteoarthritis (MESH:D010003), Atypical mycobacterial infection (MESH:D009165), Waldenstrom macroglobulinemia (MESH:D008258), Periarticular osteopenia (MESH:D001851), psoriatic arthritis (MESH:D015535), pain (MESH:D010146), discoloration (MESH:D014075), cystic (MESH:D018297), Gout (MESH:D006073), edema (MESH:D004487), Kaposi sarcoma (MESH:D012514), Cryoglobulinemia (MESH:D003449), infectious (MESH:D003141), granulomas (MESH:D006099), Infection (MESH:D007239), Granulomatous inflammation (MESH:D007249) - **Chemicals:** monosodium urate (MESH:D014527), Methotrexate (MESH:D008727), infliximab (MESH:D000069285), adalimumab (MESH:D000068879), Sulfasalazine (MESH:D012460) - **Species:** Homo sapiens (human, species) [taxon 9606], Human gammaherpesvirus 8 (no rank) [taxon 37296] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12310060/full.md ## Figures 2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12310060/full.md ## References 5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12310060/full.md --- Source: https://tomesphere.com/paper/PMC12310060