# Association between lifestyle-related factors and low back pain: Evidence from a Japanese population–based study

**Authors:** Soya Kawabata, Noriaki Kurita, Takuya Nikaido, Ryoji Tominaga, Yuji Endo, Nobuyuki Fujita, Shin-ichi Konno, Seiji Ohtori, Hiroshi Hashizume, Hiroshi Hashizume, Hiroshi Hashizume

PMC · DOI: 10.1371/journal.pone.0328684 · PLOS One · 2025-07-30

## TL;DR

This study finds that lifestyle factors like smoking and BMI are linked to low back pain severity and chronicity in a Japanese population.

## Contribution

The study provides new evidence on specific lifestyle-related factors associated with low back pain severity and chronicity in Japan.

## Key findings

- Smoking is significantly associated with both severity and chronicity of low back pain.
- Dyslipidemia is linked to increased severity of low back pain.
- Higher BMI and lack of exercise are also associated with more severe low back pain.

## Abstract

Low back pain (LBP) is a major public health issue, and lifestyle-related factors (LRFs) are increasingly recognized as key contributors to LBP. However, comprehensive studies using recent data concerning the association between LBP and LRFs remain limited. In this study, a nationally representative sample of Japanese adults were surveyed to evaluate the relationship between LRFs and LBP and to explore how these factors relate to both the severity and chronicity of LBP. A cross-sectional nationwide survey was conducted among 5000 randomly selected Japanese adults aged 20–90 years; valid responses were obtained from 2188. Participants were analyzed using three different methods: (1) those with or without current LBP, (2) those with no/mild or moderate/severe pain, and (3) those with or without chronic LBP. Key LRFs included body mass index, alcohol consumption, smoking, exercise habits, comorbidities (dyslipidemia, diabetes, and hypertension), and self-image regarding body shape. Multivariable logistic regression analysis revealed that current LBP was significantly associated with body mass index (odds ratio [OR]=1.04, 95% confidence interval [CI]: 1.00–1.07), alcohol consumption (OR=1.37, 95% CI: 1.04–1.80), smoking (OR=1.63, 95% CI: 1.21–2.20), and dyslipidemia (OR=1.51, 95% CI: 1.06–2.13), and the severity of LBP was associated with smoking (OR=1.77, 95% CI: 1.19–2.64), lack of exercise (OR=1.55, 95% CI: 1.10–2.15), and dyslipidemia (OR=1.64, 95% CI: 1.06–2.55). In addition, smoking was the only LRF significantly associated with chronic LBP (OR=1.70, 95% CI: 1.23–2.34). Multiple LRFs are associated with the prevalence of LBP. Stratified analysis provided deeper insight into specific risk factors for LBP. In particular, dyslipidemia is linked to pain severity, whereas smoking is associated with both severity and chronicity. Future longitudinal studies should focus on the influence of these key LRFs on onset, severity, and chronicity of LBP.

## Linked entities

- **Diseases:** dyslipidemia (MONDO:0002525), diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** underweight (MESH:D013851), lipid abnormalities (MESH:D011017), hypertension (MESH:D006973), Lumbar Spine Disorders (MESH:C535531), canal stenosis (MESH:D003251), Dyslipidemia (MESH:D050171), overweight (MESH:D050177), Obesity (MESH:D009765), weight loss (MESH:D015431), endothelial (MESH:D005642), ORCID iD (MESH:C535742), smoking (MESH:D015208), Pain (MESH:D010146), COVID-19 (MESH:D000086382), acute versus chronic pain (MESH:D059787), spinal epidural lipomatosis (MESH:D046748), inflammatory (MESH:D007249), adiposity (MESH:D018205), disc degeneration (MESH:D055959), diabetes (MESH:D003920), LRFs (MESH:D005171), chronic pain (MESH:D059350), atherosclerosis (MESH:D050197), chronic (MESH:D002908), Chronic LBP (MESH:D017116), lifestyle-related diseases (MESH:D000077733)
- **Chemicals:** alcohol (MESH:D000438), triglyceride (MESH:D014280), LDL-C (-), cholesterol (MESH:D002784)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12310045/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12310045/full.md

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Source: https://tomesphere.com/paper/PMC12310045