# First person – Rashmi Sivasengh

## TL;DR

This paper introduces a new method to study how circadian rhythms affect insulin sensitivity in muscle cells.

## Contribution

The study identifies Per3 as a novel regulator of circadian insulin sensitivity using a live-cell assay.

## Key findings

- Per3 regulates circadian insulin sensitivity in skeletal muscle cells.
- The live-cell GLUT4 translocation assay provides new insights into metabolic disease mechanisms.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Rashmi Sivasengh is first author on ‘
Live-cell GLUT4 translocation assay reveals Per3 as a novel regulator of circadian insulin sensitivity in skeletal muscle cells’, published in BIO. Rashmi is a PhD student (final year) in the lab of Dr Brendan Gabriel at University of Aberdeen, Aberdeen, UK, investigating how cellular metabolism, circadian rhythms and lipid signalling interact in the context of metabolic disease.