# First person – Qingran Huo

PMC · DOI: 10.1242/dmm.052522 · Disease Models & Mechanisms · 2025-07-07

## TL;DR

This paper discusses Qingran Huo's research on how disrupting Morrbid helps reduce bone inflammation in mice with a specific genetic deficiency.

## Contribution

The study introduces a new approach to treating autoinflammatory osteomyelitis by targeting Morrbid in Pstpip2-deficient mice.

## Key findings

- Disruption of Morrbid alleviates autoinflammatory osteomyelitis in Pstpip2-deficient mice.
- The research provides insights into potential therapeutic strategies for autoinflammatory diseases.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Qingran Huo is first author on ‘
Disruption of Morrbid alleviates autoinflammatory osteomyelitis in Pstpip2-deficient mice’, published in DMM. Qingran is a graduate student in the lab of Professor Zhigang Cai at Tianjin Medical University, Tianjin, China, investigating autoinflammatory diseases.

## Linked entities

- **Genes:** MIR4435-2HG (MIR4435-2 host gene) [NCBI Gene 541471], PSTPIP2 (proline-serine-threonine phosphatase interacting protein 2) [NCBI Gene 9050]
- **Species:** Mus musculus (taxon 10090)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12309887/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12309887/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12309887/full.md

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Source: https://tomesphere.com/paper/PMC12309887