# Neurologic Manifestations Associated with Parvovirus B19 Epidemic, Madrid, Spain, 2024

**Authors:** Cristina Veintimilla, Pilar Catalán, Agustín Estévez, Roberto Alonso, Maricela Valerio, Patricia Muñoz

PMC · DOI: 10.3201/eid3108.250278 · Emerging Infectious Diseases · 2025-08-01

## TL;DR

This paper reports on eight cases of neurological symptoms linked to parvovirus B19 in Madrid, Spain, highlighting the importance of early diagnosis and treatment.

## Contribution

The study identifies neurologic manifestations associated with parvovirus B19 in cerebrospinal fluid for the first time in this context.

## Key findings

- Eight patients with parvovirus B19 in cerebrospinal fluid exhibited neurological symptoms.
- Early recognition of the virus improved patient outcomes.
- The study spans a 10-year period at a tertiary care center in Madrid.

## Abstract

A reemergence of parvovirus B19 infections in Spain in early 2024 prompted a 10-year review of the virus at a tertiary center. We identified 8 case-patients with neurologic manifestations who had parvovirus B19 in cerebrospinal fluid. Early recognition and management of parvovirus B19–associated neurologic conditions will help yield favorable outcomes.

## Full-text entities

- **Diseases:** parvovirus B19 infections (MESH:D016731)
- **Species:** Human parvovirus B19 (no rank) [taxon 10798], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12309755/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12309755/full.md

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Source: https://tomesphere.com/paper/PMC12309755