# Primary central nervous system mucosa-associated lymphoid tissue lymphoma: a diagnostic challenge

## TL;DR

This paper discusses a rare case where a brain tumor was initially mistaken for meningioma but was later diagnosed as a primary CNS MALT lymphoma, highlighting the importance of accurate diagnosis for proper treatment.

## Contribution

The paper presents a case study emphasizing the diagnostic challenges of distinguishing primary CNS MALT lymphoma from meningioma.

## Key findings

- A 69-year-old woman's tumor was initially suspected to be meningioma but was diagnosed as primary CNS MALT lymphoma.
- The case highlights the importance of recognizing imaging characteristics to avoid misdiagnosis.
- Secondary cutaneous tumor infiltration was observed, delaying adjuvant radiotherapy.

## Abstract

Primary central nervous system (CNS) mucosa-associated lymphoid tissue (MALT) lymphoma is a rare condition frequently mistaken for meningioma. Since these conditions require distinct treatment approaches, recognizing their imaging characteristics is essential for accurate clinical decision-making. A 69-year-old woman presented with headaches and forehead swelling, prompting MRI of the CNS. Suspecting an intracranial meningioma, the tumour board recommended surgical resection. However, histopathological analysis identified the lesion as a primary CNS MALT lymphoma. Follow-up revealed secondary cutaneous tumour infiltration, leading to a delay in adjuvant radiotherapy. Understanding the differential diagnoses of meningioma is critical for neuroradiologists and neurosurgeons to ensure appropriate treatment planning. This case highlights a misdiagnosis of meningioma that was ultimately identified as a primary CNS MALT lymphoma, emphasizing key imaging and clinical characteristics essential for distinguishing between the most important differential diagnoses of primary CNS MALT lymphoma.