# Meigs'‐Like Syndrome Secondary to Remnant Ovarian Tissue in a Cat

**Authors:** Clara Galvani, Silvia Bigi, Francesca Saponaro, Giulia Selmi, Matteo Ganapini, Maurizio Longo

PMC · DOI: 10.1111/jvim.70168 · Journal of Veterinary Internal Medicine · 2025-07-30

## TL;DR

A spayed cat showed symptoms similar to Meigs' syndrome in humans, caused by leftover ovarian tissue, and fully recovered after surgery.

## Contribution

This is the first reported case of Meigs' like syndrome in a cat due to remnant ovarian tissue.

## Key findings

- The cat had pleural and abdominal effusions along with an ovarian mass.
- Surgical removal of the mass and uterus led to full recovery.
- Histology confirmed normal ovarian tissue and uterine hyperplasia.

## Abstract

A 4‐year‐old spayed female domestic shorthair cat was evaluated for a three‐day history of dyspnea and lethargy. Abdominal ultrasonography and thoracic radiographs revealed the presence of abdominal and pleural effusions, along with both uterine horns and a rounded mass in the pelvic abdomen. Both effusions were compatible with modified transudates rich in protein and negative for infectious disease. The mass and uterus were surgically removed, and histology revealed a normal cycling ovary and uterine glandular hyperplasia. At the two‐week follow‐up after surgery, the effusion had completely disappeared, and the cat had fully recovered. In human medicine, Meigs' syndrome is characterized by the triad of pleural and abdominal effusions along with ovarian mass, most commonly fibromas. This is a report describing a Meigs' like syndrome in a young cat with ovarian remnant tissue.

## Linked entities

- **Diseases:** Meigs' syndrome (MONDO:0017799)

## Full-text entities

- **Genes:** AMH [NCBI Gene 101080263], SERPINC1 (serpin family C member 1) [NCBI Gene 462] {aka AT3, AT3D, ATIII, ATIII-R2, ATIII-T1, ATIII-T2}, VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}, MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}, AMH (anti-Mullerian hormone) [NCBI Gene 268] {aka MIF, MIS}, FGB (fibrinogen beta chain) [NCBI Gene 2244] {aka HEL-S-78p}, USF2 (upstream transcription factor 2, c-fos interacting) [NCBI Gene 7392] {aka FIP, bHLHb12}, FDPS (farnesyl diphosphate synthase) [NCBI Gene 2224] {aka FPPS, FPS, POROK9}
- **Diseases:** ovarian tumors (MESH:D010051), hypoglobulinemia (MESH:C565765), Tjalma syndrome (MESH:D013577), fibroma (MESH:D005350), venous obstruction (MESH:D006502), abdominal effusion (MESH:D000007), neutrophilia (MESH:C563010), pulmonary atelectasis (MESH:D001261), Pleural effusion (MESH:D010996), dyspnea (MESH:D004417), Brenner tumors (MESH:D001948), hyperplastic (MESH:D000082242), granuloma cell tumors (MESH:D006101), pericardial effusion (MESH:D010490), lethargy (MESH:D053609), hyperglycemia (MESH:D006943), ascites (MESH:D001201), Demons-Meigs' syndrome (MESH:D008538), metastasis (MESH:D009362), hyperplasia (MESH:D006965), systemic lupus erythematosus (MESH:D008180), benign genital tumors (MESH:D009369), tachypnea (MESH:D059246), respiratory distress (MESH:D012128), ORS (MESH:D010049), bicavitary effusion (MESH:D000080324), hypoproteinemia (MESH:D007019), adhesions (MESH:D000267), infectious disease (MESH:D003141), benign and malignant tumors (MESH:D018198), edema (MESH:D004487), hypoalbuminemia (MESH:D034141)
- **Chemicals:** Dechra (-), Dexdomitor (MESH:D020927), Butorphanol (MESH:D002077), Propofol (MESH:D015742)
- **Species:** Felis catus (cat, species) [taxon 9685], Homo sapiens (human, species) [taxon 9606], Gammacoronavirus (genus) [taxon 694013]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12308068/full.md

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Source: https://tomesphere.com/paper/PMC12308068