# The US Deprescribing Research Network: a network to catalyze deprescribing science

**Authors:** Raha Shahroodi, Jonathan D. Norton, Cynthia M. Boyd, Michael A. Steinman

PMC · DOI: 10.3389/fmed.2025.1622200 · Frontiers in Medicine · 2025-07-16

## TL;DR

The US Deprescribing Research Network aims to improve healthcare for older adults by researching how to safely stop unnecessary medications.

## Contribution

The paper introduces the US Deprescribing Research Network to advance deprescribing science for older adults.

## Key findings

- Deprescribing is essential for reducing medication-related harm in older adults.
- The US Deprescribing Research Network was established to enhance deprescribing research quality and impact.
- Future research directions aim to optimize medication use and improve healthcare outcomes.

## Abstract

Deprescribing plays a critical role in ensuring safe and effective healthcare for older adults, including but not limited to those with vulnerabilities such as multimorbidity and dementia, which increase the risk of harm from unnecessary medications. However, much is unknown on how to safely and effectively stop medications. In response, the US Deprescribing Research Network (USDeN) was created with a mission of enhancing the quality, volume, and real-world impact of research aimed at optimizing medication use among older adults. This Perspective explores the rationale for its creation, the principles and ideas that animate its work, its impacts on research, and future directions for deprescribing research. By advancing research in this area, we aim to improve healthcare outcomes and reduce medication-related harm among older adults.

## Full-text entities

- **Diseases:** dementia (MESH:D003704)
- **Chemicals:** benzodiazepine (MESH:D001569)
- **Species:** Crohivirus B (no rank) [taxon 2169854], Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12307437/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12307437/full.md

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Source: https://tomesphere.com/paper/PMC12307437