# Association between dyslexia and overweight/obesity among Chinese children: findings from a cross-sectional study

**Authors:** Bing Zhu, Hong Fan, Min Wang, Kaiheng Zhu, Yanan Feng, Haoxue Wang, Qi Jiang, Zhen Xiang, Qianhui Chen, Ziyan Xiong, Ranran Song

PMC · DOI: 10.3389/fped.2025.1600848 · Frontiers in Pediatrics · 2025-07-16

## TL;DR

This study finds that Chinese children with dyslexia are more likely to be obese compared to non-dyslexic children, especially girls.

## Contribution

The study is among the first to investigate the link between dyslexia and obesity in Chinese children, revealing a significant association.

## Key findings

- Dyslexic children had a 23.9% obesity rate compared to 15.4% in non-dyslexic children.
- After adjusting for confounders, dyslexic children were 1.57 times more likely to be obese.
- The association between dyslexia and obesity was stronger in girls than in boys.

## Abstract

Extensive studies have consistently reported associations between neurodevelopmental disorders and overweight/obesity. However, limited research addressed the weight status of children with dyslexia. Therefore, this study aimed to explore the association between dyslexia and overweight/obesity among Chinese children.

7,116 children were recruited from the Tongji Reading Environment and Dyslexia research program, including 197 dyslexic and 6,919 non-dyslexic children. The standard “Screening for overweight and obesity among school-aged children and adolescents (WS-T 586-2018)” was utilized to define overweight and obesity. Logistic regression models were employed to examine the association between dyslexia and overweight/obesity.

Among dyslexic children, 18.8% were overweight and 23.9% were obese. Among non-dyslexic children, 17.3% were overweight and 15.4% were obese. The proportion of obesity among dyslexic children was significantly higher than that among non-dyslexic children (P = 0.001). After adjusting for all potential confounders, children with dyslexia were more likely to be obese (OR = 1.57, 95% CI: 1.10-2.24). Analyses stratified by sex indicated that such associations were more significant among girls. No significant association was found between dyslexia and overweight.

This cross-sectional study provides evidence that dyslexic children had significantly higher odds of obesity. This finding emphasizes the urgent need for heightened awareness and strategies targeted to mitigate excess body weight for this special population.

## Linked entities

- **Diseases:** dyslexia (MONDO:0005489), obesity (MONDO:0011122)

## Full-text entities

- **Genes:** DRD2 (dopamine receptor D2) [NCBI Gene 1813] {aka D2DR, D2R}, BDNF (brain derived neurotrophic factor) [NCBI Gene 627] {aka ANON2, BULN2}
- **Diseases:** depression (MESH:D003866), Overweight and Obesity (MESH:D050177), ID (MESH:D008607), Learning Disabilities (MESH:D007859), excess (MESH:D006970), excess body weight (MESH:D001835), brain injury (MESH:D001930), executive dysfunction (MESH:D006331), epilepsy (MESH:D004827), Mental Disorders (MESH:D001523), anxiety disorders (MESH:D001008), ADHD (MESH:D001289), developmental disabilities (MESH:D002658), obese (MESH:D009765), sleep problems (MESH:D012893), ASD (MESH:D000067877), macrosomia (MESH:D005320), impaired fluent or accurate word recognition and spelling (MESH:D001037), gastrointestinal problems (MESH:D012817), Dyslexia (MESH:D004410), weight gain (MESH:D015430), visual and auditory impairment (MESH:D014786), autistic (MESH:D001321), motor problems (MESH:D019973), unhealthy eating problems (MESH:D001068)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** Val66Met

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12307394/full.md

## References

51 references — full list in the complete paper: https://tomesphere.com/paper/PMC12307394/full.md

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Source: https://tomesphere.com/paper/PMC12307394