# Eczematous Neurodermatitis Following Total Knee Arthroplasty: Expanding Awareness of a Rare and Underdiagnosed Postoperative Dermatologic Complication

**Authors:** Eliana Jolkovsky, Erik Zeegen, Iris Ahronowitz

PMC · DOI: 10.7759/cureus.86989 · Cureus · 2025-06-29

## TL;DR

A rare skin condition called SKINTED can occur after knee surgery, causing eczema-like symptoms that can be treated with corticosteroids.

## Contribution

This paper highlights SKINTED as a new, underdiagnosed complication of knee surgery and emphasizes the importance of increased awareness among medical professionals.

## Key findings

- SKINTED presents as eczematous dermatitis with altered skin sensation after knee surgery.
- Topical corticosteroids effectively resolved symptoms in a reported case.
- Raising awareness can prevent misdiagnosis and unnecessary treatments.

## Abstract

SKINTED (surgery of the knee, injury to the infrapatellar branch of the saphenous nerve, traumatic eczematous dermatitis) is a recently described dermatological condition resulting from injury to the infrapatellar branch of the saphenous nerve (IPBSN) during knee surgery. This rare and underdiagnosed surgical complication characteristically presents as an eczematous eruption within an area of altered skin sensation in the distribution of IPBSN innervation. We describe a case of SKINTED in a 64-year-old female patient who presented with localized dermatitis, severe pruritus, intermittent pain, and mild numbness of her knee six months following total knee arthroplasty. Dermatologic evaluation led to a clinical diagnosis of SKINTED, and treatment with topical corticosteroids successfully resolved her symptoms. This case reinforces the need to consider SKINTED in appropriate patients. Increased awareness of this condition among both dermatologists and orthopedic surgeons can prevent misdiagnoses and unnecessary use of antibiotics, biopsies, and imaging, as well as help alleviate patient anxiety.

## Linked entities

- **Diseases:** eczematous dermatitis (MONDO:0004980)

## Full-text entities

- **Diseases:** cutaneous lesions (MESH:D009059), Eczematous Neurodermatitis (MESH:D017443), fecal incontinence (MESH:D005242), fevers (MESH:D005334), Gilbert's disease (MESH:D005878), incontinence (MESH:D014549), joint effusion (MESH:D000080324), immune dysregulation (OMIM:614878), gastric metaplasia (MESH:D008679), nerve (MESH:C537568), osseous abnormalities (MESH:D010001), Crohn's disease (MESH:D003424), metal (MESH:D013651), synovitis (MESH:D013585), infection (MESH:D007239), anal sphincter injury (MESH:C538254), allergic reaction (MESH:D004342), hypoesthesia (MESH:D006987), Pruritus (MESH:D011537), osteoarthritis (MESH:D010003), pain (MESH:D010146), myocardial bridge (MESH:D054084), basal cell carcinoma (MESH:D002280), injury to the infrapatellar branch of the saphenous nerve (MESH:D000080902), hypersensitivity rash (MESH:D005076), polyp (MESH:D011127), anxiety (MESH:D001007), neurodermatitis (MESH:D009450), radiculopathy (MESH:D011843), postoperative complication (MESH:D011183), erythema (MESH:D004890), Sensory loss (MESH:C580162), muscle spasms (MESH:D013035), IPBSN injury (MESH:D014947), eczematous dermatitis (MESH:D004485), allergic contact dermatitis (MESH:D017449), squamous cell carcinoma (MESH:D002294), fungal infection (MESH:D009181), ADD (MESH:D003872), cellulitis (MESH:D002481), coronary artery disease (MESH:D003324), knee effusions (MESH:D007718), knee pain (MESH:D046788), skin blistering (MESH:D001768), diarrhea (MESH:D003967), Dermatologic Complication (MESH:D000168)
- **Chemicals:** metoprolol succinate (MESH:D008790), ascorbic acid (MESH:D001205), vitamin D (MESH:D014807), steroid (MESH:D013256), alcohol (MESH:D000438), docusate (MESH:D004143), hydrocortisone (MESH:D006854), estradiol (MESH:D004958), ondansetron (MESH:D017294), triamcinolone (MESH:D014221), progesterone (MESH:D011374), chondroitin (MESH:D002807), glucosamine (MESH:D005944), metal hypersensitivity dermatitis (-), tramadol (MESH:D014147), methocarbamol (MESH:D008721)
- **Species:** Nicotiana tabacum (American tobacco, species) [taxon 4097], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12307027/full.md

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Source: https://tomesphere.com/paper/PMC12307027