# Acute Hemichorea in a Young Patient Secondary to Ischemic Infarction in the Right Lentiform Nucleus: A Case Report

**Authors:** Yee Mon Thu, Ali Altahiry, Christos Nikola, Bader Mohamed

PMC · DOI: 10.7759/cureus.86969 · Cureus · 2025-06-29

## TL;DR

A young man developed sudden left-sided involuntary movements and vision loss due to a brain infarction, which improved after treatment.

## Contribution

This case report highlights hemichorea as a rare manifestation of acute ischaemic stroke in young patients.

## Key findings

- A 31-year-old male presented with sudden-onset left-sided hemichorea and homonymous hemianopia.
- Brain MRI revealed an acute right lentiform infarct involving the globus pallidus.
- Antiplatelet therapy led to marked improvement within 24 hours.

## Abstract

Chorea is a hyperkinetic movement disorder characterised by brief, unpredictable, dance-like involuntary movements involving multiple body parts. Hemichorea is its unilateral variant, affecting one side of the body. Both can arise from diverse aetiologies, including genetic, vascular, metabolic, autoimmune, drug-induced, and infectious causes. We report the case of a 31-year-old male with no significant past medical history who developed sudden-onset, left-sided hemichorea and homonymous hemianopia. Brain MRI demonstrated an acute right lentiform infarct, predominantly involving the globus pallidus. The patient improved markedly within 24 hours following the initiation of antiplatelet therapy. Further investigations revealed a Stage 2A-shunt patent foramen ovale, deemed the likely aetiology. This case underscores the importance of recognising hemichorea as a rare but possible manifestation of acute ischaemic stroke and highlights the need for comprehensive diagnostic evaluation in young patients presenting with atypical stroke symptoms.

## Full-text entities

- **Genes:** F2 (coagulation factor II, thrombin) [NCBI Gene 2147] {aka PT, RPRGL2, THPH1}, F5 (coagulation factor V) [NCBI Gene 2153] {aka FVL, PCCF, RPRGL1, THPH2, fV}, SERPINC1 (serpin family C member 1) [NCBI Gene 462] {aka AT3, AT3D, ATIII, ATIII-R2, ATIII-T1, ATIII-T2}
- **Diseases:** cerebral infarct (MESH:D002544), Paradoxical Embolism (MESH:D019320), dysarthria (MESH:D004401), arrhythmia (MESH:D001145), joint pain (MESH:D018771), fever (MESH:D005334), swelling (MESH:D004487), neurodegenerative syndromes (MESH:D020271), Stroke (MESH:D020521), vascular (MESH:D057772), drug-induced dyskinesias (MESH:D004409), renal or hepatic failure (MESH:D017093), ischaemic or haemorrhagic strokes (MESH:D002543), Infection (MESH:D007239), hyperkinetic (MESH:D006948), metabolic abnormalities (MESH:D008659), systemic lupus erythematosus (MESH:D008180), non-ketotic hyperglycaemia (MESH:D020158), limb or facial weakness (MESH:D018908), facial asymmetry (MESH:D005146), Huntington's disease (MESH:D006816), viral encephalitis (MESH:D018792), Chorea (MESH:D002819), autoimmune encephalitis (MESH:D020274), endocrinopathies (MESH:C567425), hepatitis C (MESH:D019698), sensory disturbances (MESH:D012678), hemiballismus (MESH:D020820), hyperglycemia (MESH:D006943), rash (MESH:D005076), thrombophilia (MESH:D019851), intracranial artery occlusion (MESH:D001157), cerebrovascular symptom (MESH:D002561), cardioembolic strokes (MESH:D000083262), cryptogenic stroke (MESH:D000083242), ischaemic lesions (MESH:D018917), neuroleptics (MESH:D009459), Acute Hemichorea (MESH:D000208), systemic disorders (MESH:D009422), embolic (MESH:D004617), cytotoxic oedema (MESH:C536897), hepatitis B (MESH:D006509), thyroid dysfunction (MESH:D013959), cardiac thrombus (MESH:D013927), blurred vision (MESH:D014786), basal ganglia dysfunction (MESH:D001480), HIV (MESH:D015658), syphilis (MESH:D013587), movement disorders (MESH:D009069), dizziness (MESH:D004244), PFO (MESH:D054092), basal ganglia infarction (MESH:D007238), homonymous hemianopia (MESH:D006423), DVT (MESH:D020246), autoimmune (MESH:D001327), loss of consciousness (MESH:D014474), nutritional deficiencies (MESH:D044342), ischemic (MESH:D002545)
- **Chemicals:** vitamin B12 (MESH:D014805), Atorvastatin (MESH:D000069059), lipid (MESH:D008055), triglyceride (MESH:D014280), clopidogrel (MESH:D000077144), alcohol (MESH:D000438), GABA (MESH:D005680), cholesterol (MESH:D002784), antiplatelet (-), thiamine (MESH:D013831), aspirin (MESH:D001241), niacin (MESH:D009525)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A1C

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12306588/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12306588/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12306588/full.md

---
Source: https://tomesphere.com/paper/PMC12306588