Exploring bioadhesion: insight on innovative strategies to investigate bioadhesive scaffolds
Marta Pollini, Eleonora Bianchi, Marco Ruggeri, Barbara Vigani, Silvia Rossi, Giuseppina Sandri
TL;DR
This review explores techniques for evaluating bioadhesive scaffolds used in biomedical applications, especially wound healing.
Contribution
The paper provides a comprehensive overview of traditional and innovative methods for assessing bioadhesion and mucoadhesion in biomedical materials.
Findings
Traditional and recent methods for evaluating bioadhesion and mucoadhesion are reviewed.
The paper highlights the importance of selecting appropriate biological substrates for testing bioadhesion.
Biomaterials and their adhesion mechanisms are discussed in the context of biomedical applications.
Abstract
In the pharmaceutic field, materials with enhanced bioadhesive properties have been widely employed to produce scaffolds with deep interaction and adhesion to the biological surfaces, preventing them from dislocation and promoting cell homing, proliferation and growth. Parallelly, mucoadhesion has been extensively used to increase formulation retention onto the mucosal surface. This review aims to describe the most appropriate and relevant techniques to evaluate scaffolds bioadhesion and mucoadhesion for biomedical application, and more in details, in wound healing treatment. Different methods will be reviewed and described in order to provide an overview of the traditional approaches and the most innovative and recent tools. In addition, critical considerations on the variety of biological substrates that could be used will be reported to underline the different alternatives for…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsBone Tissue Engineering Materials · 3D Printing in Biomedical Research · Orthopaedic implants and arthroplasty