# Outcome after isolated medial patellofemoral ligament reconstruction is dependent on age but not on body mass index or gender

**Authors:** Olivia Bohe, Antonia Schneider, Armin Runer, Sebastian Siebenlist, Andrea Achtnich

PMC · DOI: 10.1002/jeo2.70332 · 2025-07-29

## TL;DR

This study finds that older age at surgery affects outcomes after MPFL reconstruction, but BMI and gender do not.

## Contribution

The study identifies age as a significant factor influencing functional outcomes after MPFL reconstruction, independent of BMI or gender.

## Key findings

- Older age at surgery correlates with worse functional outcomes after MPFL reconstruction.
- No significant differences in outcomes were found between genders or based on BMI.
- Most patients reported high satisfaction with the surgical results.

## Abstract

Medial patellofemoral ligament (MPFL) reconstruction is the most used surgical technique in the treatment of patellofemoral instability. However, the role of patient specific factors like age, sex and body mass index (BMI) at surgery is being increasingly discussed. The aim of this study was to study the influence of these factors with regards to functional outcomes and redislocation rates.

All patients with patellofemoral instability, who were treated with isolated MPFL reconstruction surgery between 01/2017 to 01/2022, were included. Patients with pathologic risk factors, high‐grade cartilage damage, prior surgeries and age <14 years were excluded. Demographic information and information concerning surgery, complications and history were collected. Patient reported outcome measures (PROMs) were collected preoperatively, after 6 and 12 months postoperatively and at final follow‐up using multiple standardised scores (knee injury and osteoarthritis outcome score, International Knee Documentation Committee [IKDC], Tegner activity scale, Kujala, BANFF).

Of the 62 patients included in this study 42 (67.7%) were female with a mean age of 24.8 ± 7.6 years and a mean BMI of 24.5 ± 4.7 kg/m2 at the time of surgery. Final follow‐up was 42.3 ± 23.4 months. Fifty‐four (90.3%) patients were satisfied with the functional outcome, four (6.5%) patients suffered recurrent dislocation.

Overall, the functional outcome was very good in our study population (e.g., Kujala 87.0 ± 10.5, IKDC 76.4 ± 13.7). In the subgroup analysis, there were no significant differences in the functional outcome between women and men (e.g., Kujala score: 87.2 ± 11.4 vs. 86.4 ± 7.8, p = 0.81) and there was no correlation with BMI at time of surgery (e.g., Kujala, r = 0.11, p = 0.53). However, statistically significant correlations were detected in functional outcome with the age at surgery.

Older age at the time of surgery has a highly significant negative correlation with the functional outcome after isolated MPFL reconstruction. Therefore, surgeons must be highly vigilant and identify high‐risk patients even before surgery and necessary MPFL reconstruction should not be delayed.

Level III, retrospective cohort study.

## Full-text entities

- **Genes:** MSLNL (mesothelin like) [NCBI Gene 401827] {aka C16orf37, MPFL}
- **Diseases:** re-dislocation (MESH:D000084063), bony incongruence (MESH:D018213), deformities (MESH:D009140), chondral injuries (MESH:D014947), rotational deformity of the femur (MESH:D009759), dislocation (MESH:D004204), knee injury (MESH:D007718), anterior knee pain (MESH:D046788), C and D (MESH:D019701), ICRS grade III or IV (MESH:D005909), impaired range of motion (MESH:D009041), knee joint stiffness (MESH:D000092443), valgus malalignment (MESH:D017760), osteoarthritis (MESH:D010003), instability (MESH:D043171), Patellar dislocations (MESH:D031222), pain (MESH:D010146), trochlear dysplasia (MESH:D020432), cartilage damage (MESH:D002357), patella alta (MESH:D000092462), CDI (MESH:D020790), PASS (MESH:D010302)
- **Chemicals:** S-NP (MESH:D009405), Arthrex (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12305113/full.md

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Source: https://tomesphere.com/paper/PMC12305113