# Bispecific antibody targeting CD40 and HER2 potentiates therapeutic efficacy by reprogramming macrophages within the tumour microenvironment

**Authors:** Na Li, Ruonan Li, Qiongqiong Ma, Xiaoqi Zhang, Wenxuan Ma, Yi Wang, Baoxin Duan, Kailu Yang, Dongping Zhang, Jiashuo Zhang, Manping Gu, Yaxing Wu, Jiajin Sun, Huawei Wang, Anqi Li, Fuquan Chen, Yiyang Bai, Yujie Tian, Xin Li, Yingbin Yan, Wei Wang, Hongkai Zhang, Yuan Wang

PMC · DOI: 10.1002/ctm2.70428 · 2025-07-29

## Full-text entities

- **Genes:** ERBB2 (erb-b2 receptor tyrosine kinase 2) [NCBI Gene 2064] {aka CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19}, CD40 (CD40 molecule) [NCBI Gene 958] {aka Bp50, CDW40, TNFRSF5, p50}
- **Diseases:** tumour (MESH:D009369)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12304727/full.md

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Source: https://tomesphere.com/paper/PMC12304727