# Landing Biomechanics in Patients 2 Years After Augmented ACL Repair and 2 Years After Hamstring Autograft ACL Reconstruction Compared With Controls

**Authors:** Linda Bühl, Sebastian Müller, Corina Nüesch, Florian Samuel Halbeisen, Annegret Mündermann, Christian Egloff

PMC · DOI: 10.1177/23259671251358386 · 2025-07-25

## TL;DR

This study compares leg biomechanics in patients who had two different types of ACL surgery and finds that both show lasting differences compared to healthy controls.

## Contribution

The study provides new empirical evidence on long-term biomechanical outcomes of ACL-IB compared to ACLR and controls.

## Key findings

- Patients who underwent ACL-IB showed greater leg differences in knee flexion angle and moment than controls.
- Both ACL-IB and ACLR patients had significant biomechanical differences in landing mechanics two years post-surgery.
- ACL-IB patients had lower peak knee flexion moment in the involved leg compared to control legs.

## Abstract

InternalBrace-augmented anterior cruciate ligament repair (ACL-IB) is believed to restore natural knee mechanics. However, there is a dearth of data on in vivo leg biomechanics after ACL-IB and comparability with gold standard surgery.

To (1) investigate differences in sagittal and frontal landing biomechanics of the legs in patients after ACL-IB (Comparison I) and after anterior cruciate ligament reconstruction (ACLR; Comparison II), compare the involved legs with controls (Comparison III), and (2) identify leg differences that were greater than those typically observed in controls.

Cross-sectional study, Level of Evidence 3.

A total of 29 patients who had ACL-IB, 27 sex- and age-matched patients who had ACLR, and 29 matched controls were asked to perform single-leg hops (SLH) for maximum forward distance 2 years postoperatively, assessed by marker-based motion analysis. Sagittal (hip, knee, and ankle) and frontal (hip and knee) plane angles and peak moments, joint work contribution, and peak vertical ground-reaction force and loading rates during landing were calculated. Differences between the involved and uninvolved legs in patients (paired t tests) and between the involved legs in patients and the nondominant legs in controls (1-way analysis of variance) were analyzed. To determine whether these differences exceeded the typical variation seen in the control legs, we compared the overlap of the 95% CIs of the differences with the 95% CIs of the within-control differences (the nondominant versus dominant leg).

Patients who underwent ACL-IB (ACL-IB group) and ACLR (ACLR group) showed significant differences in their legs’ SLH landing biomechanics. Only leg differences in the ACL-IB group were greater than those in in the control group (no overlap): smaller peak knee flexion angle (leg difference: −8.3° [95% CI, −13 to −3.7]; d = −0.85; P = .001; controls [95% CI, −1.7 to 4.2]) and lower peak knee flexion moment (−0.60 Nm/kg [95% CI, −0.72 to −0.31]; d = −0.72; P < .001; controls [95% CI, −0.06 to 0.35]) in the involved compared with the uninvolved leg; and lower peak knee flexion moment in the involved leg compared with control legs (−0.50 Nm/kg [95% CI, −1 to −0.07]; d = −0.71; P = .020).

Persistent differences in SLH landing biomechanics 2 years after ACL surgery suggest that ACL ruptures cause alterations that cannot be restored by augmented repair or reconstruction alone. The greater differences between the legs in the ACL-IB group than those typically seen within controls highlight the need for further research to understand the full potential or limitation of ACL preservation techniques.

## Full-text entities

- **Genes:** HOPX (HOP homeobox) [NCBI Gene 84525] {aka CAMEO, HOD, HOP, LAGY, NECC1, OB1}
- **Diseases:** knee joint degeneration (MESH:D000092443), SLH (MESH:D012640), ACL ruptures (MESH:D012421), ACL injuries (MESH:D000070598), ORCID iDs (MESH:C535742), anterior knee laxity (MESH:D046788), or knee ligament injury (MESH:D007718), IB (MESH:C567452)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12304590/full.md

---
Source: https://tomesphere.com/paper/PMC12304590