Efficacy and safety of modified dual knife fistulotomy in complex ERCP cases involving type 3 papilla

TL;DR

A modified dual knife fistulotomy technique improves success rates in difficult ERCP procedures involving type 3 papilla without increasing risks.

Contribution

A modified dual knife fistulotomy technique is introduced and shown to be effective for challenging biliary cannulation in type 3 papilla.

Findings

The success rate of biliary cannulation increased from 81.3% to 99.7% with the modified dual knife fistulotomy.

The technique achieved a 95.2% technical success rate without serious adverse events.

Abstract

Cannulating protruding or pendulous type 3 papilla presents a higher level of difficulty in ERCP. Although pre-cutting papillotomy is a viable strategy, it is not without challenges. To overcome this issue, we developed a modified dual knife fistulotomy technique. The primary objective of this study was to assess the feasibility of a modified dual knife fistulotomy technique for achieving challenging biliary cannulation in type 3 papilla.

This retrospective study investigated consecutive patients who underwent ERCP and dual knife fistulotomy for challenging biliary cannulation from 2017 to 2023. The study assessed the rates of technical success and adverse events related to dual knife fistulotomy during ERCP.

During the study period, a total of 380 patients with native type 3 papilla underwent ERCP. The initial success rate of biliary cannulation using the standard cannulation approach alone was 81.3% (309/380), which improved to 94.5% (359/380) by incorporating the double guidewire technique. Furthermore, the success rate further increased to 99.7% (379/380) with the addition of dual knife fistulotomy. Dual knife fistulotomy achieved a technical success rate of 95.2% (20/21) while no serious adverse events occurred.

Dual knife fistulotomy is an effective technique for gaining access to the biliary system in cases of unsuccessful standard cannulation of type 3 papilla, with no significant increase in the risk of adverse events.

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