# White paper – A proposal towards objective biomechanical metrics as novel endpoints to document improvements in musculoskeletal function and mobility

**Authors:** Sónia A. Alves, Nicholas M. Brisson, Alison N. Agres, Mark Heyland, Ali Mobasheri, David J. Hunter, Tobias Winkler, Georg N. Duda

PMC · DOI: 10.1016/j.ocarto.2025.100648 · Osteoarthritis and Cartilage Open · 2025-07-05

## Abstract

Image 1

## Full-text entities

- **Genes:** SAA [NCBI Gene 6287]
- **Diseases:** Osteoporosis (MESH:D010024), lower back pain (MESH:D017116), diabetic neuropathy (MESH:D003929), cognitive decline (MESH:D003072), chronic diseases (MESH:D002908), systemic diseases (MESH:D034721), articular fractures (MESH:D057072), inflammation (MESH:D007249), foot disorders (MESH:D005534), trauma (MESH:D014947), joint injuries (MESH:D000092464), MSK (MESH:D009140), bone fracture (MESH:D050723), Achilles tendon rupture (MESH:D012421), limb asymmetries (MESH:D005146), Pain (MESH:D010146), knee ligament injuries (MESH:D007718), systemic (MESH:D015619), cruciate ligament tears (MESH:D000070598), OA (MESH:D010003), cardiovascular disease (MESH:D002318), mobility impairments (MESH:D014086), Disease (MESH:D004194), CArtilage (MESH:D002357)
- **Chemicals:** DJH (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12302285/full.md

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Source: https://tomesphere.com/paper/PMC12302285