# Clinical effect of fast-track surgery on laparoscopic treatment of pediatric acute appendicitis and its effect on abdominal inflammation and stress level

**Authors:** Wen-long Liu, Shan-po Wei, Lin-feng Zou, Sheng-chuan Tian, Yan-yan Liu

PMC · DOI: 10.12669/pjms.41.7.11153 · Pakistan Journal of Medical Sciences · 2025-07-01

## TL;DR

This study shows that fast-track surgery improves recovery and reduces complications in children undergoing laparoscopic appendectomy.

## Contribution

The study demonstrates the effectiveness of fast-track surgery in pediatric laparoscopic appendectomy recovery.

## Key findings

- Fast-track surgery significantly reduced postoperative recovery time and hospital stay.
- The experimental group had lower pain scores and higher nursing satisfaction compared to the control group.
- Complications like nausea and vomiting were less frequent in the fast-track surgery group.

## Abstract

To observe the clinical effect of fast-track surgery on laparoscopic treatment of pediatric acute appendicitis and its effect on abdominal inflammation and stress level.

This was a clinical comparative study. Ninety children admitted to Baoding Hospital, Beijing Children’s Hospital Affiliated to Capital Medical University from July 2022 to December 2023 for laparoscopic appendectomy were randomly divided into the control group and the experimental group(n=45 in each group). The control cohort received routine perioperative nursing care, whereas the experimental cohort received fast-track surgery during the same perioperative period. Postoperative complications, including abdominal distension, nausea, vomiting, urinary tract infection, poor incision healing, were compared between the two cohorts. Evaluated the contrasts in stress biomarkers, including TNF α, IL-6, CRP, and serum cortisol (cort), as well as pain symptoms and satisfaction levels between the control and experimental cohorts.

The experimental cohort exhibited considerably shorter postoperative exhaust time, feeding time, getting out-of-bed time, and hospital stay compared to the control cohort, with statistically meaningful contrast(P=0.00). At 12 and 24 hours after surgery, the VAS scores in the experimental cohort were considerably lower than those in the control cohort, with a statistically meaningful contrast(P=0.00). Furthermore, the nursing satisfaction rate in the experimental cohort was considerably higher than in the control cohort, with a statistically meaningful contrast (P=0.02).

Fast-track surgery boasts a variety of benefits in the perioperative period of laparoscopic treatment of pediatric acute appendicitis, such as effectively shortening postoperative recovery time and hospital stay, reducing the occurrence of complications.

## Linked entities

- **Diseases:** acute appendicitis (MONDO:0005649)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}
- **Diseases:** vomiting (MESH:D014839), acute appendicitis (MESH:D001064), abdominal inflammation (MESH:D007249), Postoperative (MESH:D019106), pain (MESH:D010146), nausea (MESH:D009325), abdominal distension (MESH:D000007), urinary tract infection (MESH:D014552)
- **Chemicals:** cort (MESH:D006854)

## Full text

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12302109/full.md

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Source: https://tomesphere.com/paper/PMC12302109