# Prediction of the composition of urinary calculi using artificial intelligence

**Authors:** Dan Shen, Tianxiong Yang, Tao Ma, Wenzeng Yang, Hongmei Li, Zhenyu Cui

PMC · DOI: 10.12669/pjms.41.7.11360 · Pakistan Journal of Medical Sciences · 2025-07-01

## TL;DR

This study shows that AI can accurately predict the composition of urinary stones from CT scans, offering potential for clinical use.

## Contribution

The study demonstrates the effectiveness of Faster R-CNN in predicting urinary calculi composition from CT images.

## Key findings

- The model achieved an AUC of 0.843 in validation Group-I for predicting stone composition.
- Kappa values of 0.649 and 0.653 were observed for calcium oxalate and uric acid predictions in mixed calculi.
- Faster R-CNN shows strong potential for clinical application in urinary stone composition analysis.

## Abstract

To explore the capability and clinical application potential of the Faster Region-based Convolutional Neural Network (Faster R-CNN), an Artificial intelligence algorithm, in identifying the composition of urinary calculi from CT images.

This was a retrospective study. Data from 776 patients with urinary calculi treated at the Affiliated Hospital of Hebei University from August 2020 to December 2023 were collected. Patients with simple calculi were randomly divided into a model construction group and validation Group-I at a 5:1 ratio, while 60 cases of mixed calculi were randomly selected to form validation Group-II. The model construction group was employed to construct and test the performance of the Faster R-CNN model, while the validation groups were used to verify the model’s performance.

In validation Group-I, the model achieved an area under the curve (AUC) of 0.843. In validation Group-II, the kappa values for the model’s prediction of calcium oxalate and uric acid components, consistent with infrared spectroscopy analysis, were 0.649 and 0.653, respectively.

Faster R-CNN demonstrates a robust capability for quantitative prediction of the composition of urinary calculi, indicating substantial promise for clinical applications.

## Linked entities

- **Chemicals:** calcium oxalate (PubChem CID 33005), uric acid (PubChem CID 1175)

## Full-text entities

- **Diseases:** urinary calculi (MESH:D014545), calculi (MESH:D002137)
- **Chemicals:** calcium oxalate (MESH:D002129), uric acid (MESH:D014527)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12302084/full.md

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Source: https://tomesphere.com/paper/PMC12302084